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GRADE 10

Week 2
LESSON TITLE: FEEDBACK MECHANISMS INVOLVED IN REGULATING PROCESSES IN THE FEMALE REPRODUCTIVE
SYSTEM
TOPIC: Female Cycles
The menstrual cycle is the monthly series of changes a woman's body goes through in preparation for the possibility of
pregnancy. Each month, one of the ovaries releases an egg — a process called ovulation. At the same time, hormonal changes
prepare the uterus for possible pregnancy.
A. MENSTRUAL CYCLE
Here are important events during the menstrual cycle:
1. The pituitary gland controls and starts the cycle.
2. The pituitary gland releases hormones that cause the egg in the ovary to mature. The luteinizing hormone (LH) initiates the
maturation of the follicles, converts ruptured follicles into corpus luteum and causes the secretion of progesterone. The follicle
stimulating hormone (FSH) assists in the maturation of the follicles and causes the secretion of estrogen from the follicles.
3. Meanwhile, the ovary itself releases a hormone called estrogen, which causes the uterine lining to increase in thickness. The
uterine lining becomes thicker so that the fertilized egg can attach to it.
4. The ovary releases an egg on day 14. Assume that no sperm is present.
5. The egg moves through the oviduct and enters the uterus.
6. Meanwhile the uterine lining continues to thicken.
7. The egg has not been fertilized, therefore, it will not attach to the uterus.
8. The thick uterine lining is no longer necessary, so the cells of the thickened uterine lining break off and leave the vagina. The
unfertilized egg is lost and some blood is lost too. This loss of cells from the uterine lining, blood, and egg is called
menstruation.
9. After menstruation, the cycle starts again.

To know more about Menstrual Cycle, see this link to Vios Fertility Institute https://viosfertility.com/blog/the-
menstrual-cycle

Figure 1: Diagram showing the different phases of Menstrual cycle and the changes occurring in uterus, Pituitary &
Ovarian hormones
B. FEEDBACK MECHANISM
A feedback mechanism is the process through which the level of one substance influences the level of
another substance. A negative feedback affects the production of hormones in the menstrual cycle. High levels of
one hormone may inhibit the production of another hormone.

Figure 2. Negative feedback mechanisms in the menstrual cycle (source: DepEd G10 Science Learner’s Material)
B.Feedback mechanisms in menstrual cycle:

1. Follicle stimulating hormone (FSH) stimulates the ovaries to release estrogen. High levels of estrogen then prevent
the further production of FSH.
2. Estrogen also stimulates the release of luteinizing hormone (LH) from the pituitary gland, which in turn controls
the production of progesterone. High levels of progesterone then inhibit the further release of LH.

Mark My Calendar
Objective:
Describe the feedback mechanisms involved in regulating processes in the female reproductive system.
Materials:
• copy of unsequenced events in menstrual cycle.
• Pencil and paper

Procedure:
1. Study the numbered diagrams/pictures of unsequenced events in menstrual cycle below.

2. Use a separate paper and copy the table below as guide in arranging the events based on its correct sequence.
Write the number only of the diagrams/pictures based on its corresponding stages/ events.
Follicular Stage

Ovulation

Luteal Stage

Menstruation

Pregnancy

Essay:
Explain why there is a high level of estrogen and progesterone once in every 28-day uterine cycle of a female.

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