Cambridge International Examinations

Cambridge International Advanced Subsidiary and Advanced Level

BIOLOGY 9700/13
Paper 1 Multiple Choice May/June 2018
1 hour
Additional Materials: Multiple Choice Answer Sheet
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Write your name, Centre number and candidate number on the Answer Sheet in the spaces provided unless
this has been done for you.
DO NOT WRITE IN ANY BARCODES.

There are forty questions on this paper. Answer all questions. For each question there are four possible
answers A, B, C and D.
Choose the one you consider correct and record your choice in soft pencil on the separate Answer Sheet.

Read the instructions on the Answer Sheet very carefully.

Each correct answer will score one mark. A mark will not be deducted for a wrong answer.
Any rough working should be done in this booklet.
Electronic calculators may be used.

This document consists of 16 printed pages.

IB18 06_9700_13/3RP
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1 Which steps are needed to find the actual width of a xylem vessel viewed in transverse section
using a ×10 objective lens?

1 Convert from mm to µm by multiplying by 10–3.

2 Calibrate the eyepiece graticule using a stage micrometer on ×4 objective lens.

3 Measure the width of the xylem vessel using an eyepiece graticule.
4 Multiply the number of eyepiece graticule units by the calibration of the eyepiece
graticule.

A 1, 2, 3 and 4
B 1 and 2 only
C 2, 3 and 4 only
D 3 and 4 only

2 The diagram shows functions of four cell structures, W, X, Y and Z.

W makes
glycolipid

Z transports function X makes

protein protein

Y makes
lipid

Which row correctly matches the cell structure with the letter representing a function?

rough smooth
Golgi body ribosome endoplasmic endoplasmic
reticulum reticulum

A W X Z Y
B X Z Y W
C Y W X Z
D Z Y W X

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3 Which cell structures produce ATP?

1 chloroplasts
2 mitochondria
3 nucleus

A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

4 When mucus is secreted from a goblet cell these events take place.

1 addition of carbohydrate to protein

2 fusion of the vesicle with the cell surface membrane
3 secretion of a glycoprotein
4 separation of a vesicle from the Golgi body

What is the sequence in which these events take place?

A 1→4→2→3

B 1→4→3→2

C 4→1→2→3

D 4→1→3→2

5 Which row could be correct for a virus?

carbohydrate DNA phospholipid lipid protein RNA

A      
B      
C      
D      

key
 = present
 = not present

6 Which size range would include most prokaryotic cells?

A B C D

1 nm 100 nm 1 µm 100 µm 1 mm

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7 Solutions of three biological molecules are tested for sugars. The table shows the colours of the
solutions after testing.

boiled with hydrochloric acid,

heated with Benedict’s
solution neutralised, then heated with
solution
Benedict’s solution

1 blue orange
2 green green
3 orange red

Which solutions contained glucose before testing?

A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

8 A solution containing equal masses of amylose and amylopectin is completely hydrolysed.

Which molecules will be found after the hydrolysis?

A α-glucose only

B β-glucose only

C equal masses of α-glucose and β-glucose

D more α-glucose than β-glucose

9 Which molecules contain the following bonds?

ester hydrogen disulfide

A amylase haemoglobin catalase

B glycerol glycogen collagen
C lipids amylopectin amylose
D phospholipids cellulose antibodies

10 Which feature of phospholipids enables a bilayer to form?

A They are insoluble in water.

B They are polar molecules.
C They have hydrophobic and hydrophilic components.
D They may contain saturated or unsaturated fatty acids.

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11 Which description is correct for collagen?

A A collagen molecule has a high proportion of the amino acid glycine, which has a very small
R group.
B A group of three collagen fibres forms a strong, insoluble coiled structure termed a triple
helix.
C Each of the collagen polypeptides in a collagen molecule has a regular spiral arrangement of
many alpha helices.
D Peptide bonds are present between amino acids of the different polypeptides forming the
collagen molecule.

12 Which statement about the properties of water is correct?

A Bonds between hydrogen atoms cause water to have a high specific heat capacity.
B The high latent heat of vaporisation of water is due to the presence of hydrogen bonds.
C The high specific heat capacity of water causes cooling during evaporation.
D Water can dissolve amylopectin as it has hydrophilic side chains.

13 Catechol is a chemical found in a number of fruits. Catechol can be oxidised to a quinone by the
enzyme catechol oxidase.

Catechol oxidase is inhibited by parahyroxybenzoic acid (PHBA) which is structurally similar to

catechol.

Catechol oxidase is also inhibited by phenylthiourea (PTU) which binds to a copper atom in the
enzyme.

How do both these inhibitors reduce the enzyme activity?

1 altering the specificity of the enzyme

2 competing with substrates for the active site

3 decreasing the Vmax of the reaction

A 1, 2 and 3 B 1 only C 2 only D 3 only

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14 Four students investigated the effect of catalase on hydrogen peroxide.

Each student started a digital clock at the beginning of the experiment and stopped the clock after
25 bubbles had been counted.

The time recorded on the digital clock is shown below.

hundredths
hours minutes seconds
of a second

00 01 33 54

Which of the times recorded by the students is appropriate for this experiment?

A 1.34 minutes
B 1 minute 33.54 seconds
C 94 seconds
D 93.54 seconds

15 What is the effect of an enzyme in an enzyme-catalysed reaction?

A decreases the activation energy and decreases the energy yield

B decreases the activation energy and has no effect on the energy yield
C increases the activation energy and increases the energy yield
D increases the energy yield and decreases the activation energy

16 The diagram shows part of the cell surface membrane.

2
4

Which components act as antigens?

A 1 and 2 B 1 and 3 C 2 and 3 D 2 and 4

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17 Which processes use energy in the form of ATP?

1 endocytosis
2 exocytosis
3 facilitated diffusion

A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

18 The diagram shows a partially plasmolysed plant cell.

solution X

Z
solution Y

What is found at Z?

A air
B solution X
C solution Y
D water

19 Which features of an organism are affected by a drug that stops mitosis?

1 cell repair
2 cell replacement
3 number of stem cells
4 tissue repair
5 tumour formation

A 1, 2, 3, 4 and 5
B 1, 2 and 3 only
C 1, 4 and 5 only
D 2, 3, 4 and 5 only

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20 Which row shows the appearance of a chromosome at the beginning of prophase of mitosis and
the number of DNA strands in the chromosome?

appearance of number of
one chromosome DNA strands

A 2

B 4

C 1

D 2

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21 The graph shows measurements taken during one mitotic cell cycle.

X
2

1
distance

0 5 10 15 20 25
time / minutes

Which stage of mitosis begins at X and which measurements are shown by curves 1 and 2?

distance between
distance between
stage centromeres of
centromeres of
beginning at X chromosomes and
sister chromatids
poles of spindle

A anaphase 1 2
B anaphase 2 1
C metaphase 1 2
D metaphase 2 1

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22 The diagram shows the outline structure of two nucleotide bases which occur in DNA.

This pair is held together by two hydrogen bonds, shown as dashed lines.

nucleotide 2

nucleotide 1

Which row correctly identifies these two nucleotide bases?

nucleotide 1 nucleotide 2

A adenine thymine
B cytosine guanine
C guanine cytosine
D thymine adenine

23 DNA polymerase catalyses condensation reactions between molecules during semi-conservative

replication of DNA.

Which two molecules are joined by DNA polymerase?

A base and base

B base and nucleotide
C nucleotide and nucleotide
D phosphate and deoxyribose

24 What occurs during each of DNA replication and transcription and translation?

1 ATP provides energy.

2 Condensation reactions occur to form a polymer.
3 Hydrogen bonds form between purine and pyrimidine bases.

A 1, 2 and 3 B 1 and 2 only C 2 only D 3 only

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25 Part of a sequence of DNA from a person with a genetic disease is:

TAGTAACCACAAAGG

The corresponding sequence of DNA from a person without this genetic disease is:

TAGTAAAAACCACAAAGG

The possible mRNA codons for some amino acids are shown in the table.

amino acid mRNA codons

1 GGU GGC GGA GGG
2 AUU AUC AUA
3 UUU UUC
4 UCU UCC UCA UCG

Which amino acid is missing from a person with this genetic disease?

A 1 B 2 C 3 D 4

26 The photomicrograph shows a section through a plant organ.

Which statement could be used to describe this organ?

A The central region of this organ has supporting tissue.

B The endodermis tissue is a thick layer around the edge of the organ.
C The epidermis tissue in this organ has unicellular extensions (trichomes).
D The xylem tissue is found in greatest density in the centre of the organ.

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27 Which diagram correctly represents part of a sieve tube element?

A B

lignified cell wall dense cytoplasm

empty lumen nucleus

sieve plate sieve plate

C D

tonoplast thin layer of cytoplasm

vacuole cellulose cell wall

sieve plate sieve plate

28 Which of the processes involved in water movement through xylem vessels depends on
hydrogen bonding between water molecules?

A adhesion
B cohesion
C evaporation
D hydrostatic pressure

29 Which statements about water movement in plants are correct?

1 Water can pass through cellulose.

2 Water cannot pass through lignin.
3 Water can pass through suberin.

A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

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30 Which blood vessel has the thickest walls?

31 Which statement about the role in the mammalian circulatory system of the heart, blood vessels
and blood is correct?

A The contraction of heart muscle causes blood to enter arteries that pump the blood to
organs, causing the formation of tissue fluid between cells before returning to the heart in
veins.
B The heart connects two sets of blood vessels so that oxygen from the lungs can be
distributed by red blood cells and wastes can be collected from tissues by blood plasma for
removal.
C The heart muscle contracts and relaxes causing blood, carrying materials from one part of
the body to another, to move through blood vessels that connect the different parts of the
body.
D The heart provides enough pressure to push blood through arteries to capillaries between
cells causing filtration of blood and the formation of tissue fluid which diffuses back into
veins.

32 What explains how the maximum uptake of oxygen occurs as blood passes through the
capillaries of the lungs?

A Each haemoglobin molecule can temporarily bind to four oxygen atoms.

B Oxyhaemoglobin formation increases the capacity of red blood cells to transport oxygen.
C The binding of the first oxygen molecule to haemoglobin decreases the molecule’s affinity for
binding other oxygen molecules.
D The dissociation of carbon dioxide from carboxyhaemoglobin allows more haemoglobin to be
available for oxygen binding.

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33 At high altitudes, the oxygen content of the air may be a third of that at sea level.

As a person climbs a mountain, their body gradually adjusts to the high altitude.

What is increased during this period of adjustment?

A the concentration of haemoglobin in the red blood cells

B the oxygen-carrying capacity of the haemoglobin
C the number of red blood cells per mm3 of blood
D the rate at which haemoglobin releases oxygen to the tissues

34 What helps to maintain a concentration gradient between blood and the air in the alveolus?

A the flow of blood through the lungs

B the presence of haemoglobin in blood cells
C the single-celled alveolar walls
D the squamous epithelium of capillaries

35 The diagram shows three features found in the tissues of the gas exchange system.

Y
goblet
ciliated
cells
epithelium
X

cartilage

Which structures of the gas exchange system could be represented at position X and at position
Y in the diagram?

1 bronchiole
2 trachea
3 bronchus

X Y

A 1 2 and 3
B 1 and 3 2
C 2 1 and 3
D 2 and 3 1

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36 Blood tests on people who regularly smoke cigarettes show that approximately 5% of their
haemoglobin carries carbon monoxide.

People who smoke e-cigarettes inhale a vapour with no carbon monoxide. A person who smokes
cigarettes regularly, switches to e-cigarettes and a blood test is carried out after a month.

Which chemical in the blood would be found in a lower concentration in this blood test?

A carbaminohaemoglobin
B carbonic anhydrase
C carboxyhaemoglobin
D hydrogencarbonate ions

37 Emphysema is a type of chronic obstructive pulmonary disease, COPD. People with emphysema
have a very low level of a plasma protein which inhibits the enzyme elastase.

Elastase breaks down the elastic fibres in the bronchioles and alveoli.

Which are effects of the low levels of inhibitor in people with emphysema?

1 alveoli do not stretch and recoil properly during inhalation and exhalation
2 blood is poorly oxygenated resulting in a rapid breathing rate
3 bronchioles collapse during exhalation trapping air in the alveoli

A 1, 2 and 3 B 1 and 3 only C 1 only D 2 and 3 only

38 Some antibiotics work by binding to ribosomes.

Which statement explains why these antibiotics kill bacteria cells but do not kill most human
cells?

A mRNA in bacteria is formed in the cytoplasm from naked DNA.

B The antibiotics cannot pass through human cell membranes.
C The codes used for amino acids in bacteria are different from those used by humans.
D The ribosomes of bacteria have a different structure from those of humans.

39 Where are antigens found?

on the surface on the surface

in blood plasma
of pathogen of macrophage

A    key
B    = antigens found
C    = antigens not found
D   

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40 The diagram allows the identification of different types of immunity.

immunity

short term long term

1

acquired by fetus from acquired by injection acquired as a result acquired by injection

the maternal circulation of antibodies into of infection by a of an attenuated
across the placenta the bloodstream pathogen pathogen
2 3

Which row correctly identifies the types of immunity labelled 1, 2 and 3?

1 2 3

A active artificial natural

B active natural artificial
C passive artificial natural
D passive natural artificial

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