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ABC of Standardized Bioactive Ingredients
ABC of Standardized Bioactive Ingredients
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Extraction
Formulation
Concentration Blending
(water or Purification
hydroethanolic) Roller Drying
Acai juice powder Total polyphenols >6% (UV 280 nm) Maltodextrin SD00020001
Health positioning: superfruit, antioxidant, beauty, reduce oxidative stress, promote nitrite reduction to NO
Organic acerola juice concentrate Natural vitamin C 17% ± 2 (HPLC) None CC00030002
Organic acerola juice powder Natural vitamin C 17% ± 1 (HPLC) Org. maltodextrin SD00030001
Organic acerola juice powder Natural vitamin C ≥ 17% (HPLC) Org. maltodextrin SD00030028
Health positioning: support immunity and energy, support iron absorption, beauty (collagen metabolism, antioxidant),
superfruit, support memory and mood, support bone and joint health (collagen metabolism)
EU claims
- Source of [natural] vitamin C: Min 12mg vit C per serving
- High in [natural] vitamin C : Min 24mg vit C per serving
EFSA health claims (min source of vit C product) :
- Vitamin C contributes to
• the normal function of the immune system
• the protection of cells from oxidative stress
• the reduction of tiredness and fatigue
• the regeneration of the reduced form of vitamin E
• normal collagen formation for the normal function of blood vessels, bones, cartilage, gums, skin and teeth
• normal energy-yielding metabolism
• normal functioning of the nervous system
• normal psychological function
- Vitamin C increases iron absorption
- Vitamin C contributes to maintain the normal function of the immune system during and after intense physical exercise (for 200mg vitamin C
daily intake)
Health positioning: glucose regulation (improve insulin sensitivity and lower blood glucose), weight loss aid (promote
satiety)
Health positioning: superfruit, antioxidant, blood circulation and blood vessel protection, beauty, reduce oxidative
stress, anti-inflammatory
Suggested dosage (literature) : 50 mg anthocyanins
EU claims USA claims
- Contains polyphenols (Min 250 mg polyphenols) - Naturally contains polyphenols (No min)
Artichoke leaf extract powder Cinnamic acids >2.5% (UV 325 nm) SD00100002
Artichoke leaf extract Cinnamic acids 2.5 - 3.5% (UV 325 nm) CC00100001 PHARMA
GRADE
Artichoke juice powder Cinnamic acids >2.5% (UV 325 nm) SD00110002
Artichoke juice concentrate Cinnamic acids >2% (UV 325 nm) CC00110001
Health positioning: Support liver and digestive functions (EU monograph for traditional herbal medicines THM),
cardiovascular health (cholesterol-lowering effect, LDL oxidation and atherosclerosis prevention, lower BP), renal water
excretion, satiety, glucose regulation, prebiotic
Suggested dosage for leaf extract (THM): 900-2400mg (in divided doses of 300-600mg)
Wild Bilberry extract powder Anthocyanins >10% (sepctro, delphinidin eq.) Glucose syrup SD01020010
Health positioning: ocular health (night vision), microcirculatory, vascular-related disorders (blood pressure, platelet
aggregation and cholesterol lowering, LDL oxidation prevention), antioxidant activity, superfruit
Health positioning: antioxidant, blood circulation, traditionally used to decrease heavy legs sensation or hemorrhoid
troubles, healthy vision
EU claims USA claims
- Contains polyphenols (Min 250 mg polyphenols) - Naturally contains polyphenols (No min)
Health positioning: antioxidant, cognition support, oral health, reduce oxidative stress, promote nitrite reduction to
NO, cardiovascular protection
EU claims
- Contains polyphenols (Min 250 mg polyphenols)
Health positioning: vitality (iron metabolism), immunity support, healthy vision, beauty (skin health), antioxidant
≥ 7% PACs SD00240027
≥ 5% PACs SD00240022
Cranberry extract powder Proanthocyanidins (BL-DMAC)
≥ 1% PACs SD00240026
Health positioning: urinary health, antioxidant, superfruit, beauty, reduce oxidative stress, promote nitrite reduction to
NO
EU claims USA claims
- Contains polyphenols (Min 250 mg polyphenols) - Naturally contains polyphenols (No min)
Suggested dosage: 1000mg/D when taken alone, 500mg/D in combination with cranberry extract
EU claims USA claims
- Can still be used as Medical device
Health positioning: weight management (satiety effect of fibers), digestion (transit stimulation), prebiotic
Health positioning: Antioxidant, supergreens, reduce oxidative stress, promote nitrite reduction to NO
Health positioning: Antioxidant, beauty, reduce oxidative stress, promote nitrite reduction to NO
Health positioning: Antioxidant, beauty (protection against cutaneous photodamage), bone health (reduce bone
resorption marker), cardiovascular protection (reduce platelet aggregation)
EU claims USA claims
- Naturally contains lycopene (Min 830mg of powder) - Naturally contains lycopene (no min)
Cardiovascular : 8.6 g Red beetroot juice powder or Literature Diets containing foods that
blood pressure concentrate standardized in review: 10+ are a good source of
reduction potassium and naturally high in NO clinical studies potassium and that are
precursors low in sodium may reduce
the risk of high blood
pressure and stroke**
**FDAMA approved health claim © DIANA FOOD, Proprietary and confidential information 45
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Health
Product Source Daily dosis Description Studies Suggested claim
positionning
Concentrated and purified Clinical
Helps maintain urinary
Urinary Tract Health 240 mg proanthocyanidins type-A from study on-
health
American cranberry. going
Glucophenol™ is a mixture of
polyphenols from the Orleans Clinical Helps improve insulin
Glucose Regulation 277-554 mg
variety of strawberries and study sensitivity
cranberries.
Orophenol™ is a standardized
blend of polyphenols obtained from Support naturally oral
Oral Health 62.5 mg In-vitro study
Canadian wild blueberries, health
cranberries, and strawberries