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Cardiovascular Disease

• CVD has been the leading cause of death in the


world
• CVD now accounts for nearly 30% of deaths
globally.
• CVD kills almost as many people yearly as the
next seven causes of death combined.
• For the last 10 years, CVD has been the leading
cause of death in Malaysia
Prevalence of Hypt in Malaysia
• ≥30 years old has increased from 32.9% in 1996
to 40.5% in 2004.
• Prevalence > in males than females
• Treatment, control and prevention is low
NHMS 2015
• Overall % = 30.3% (done among 16,017 adults in
Malaysia)
• Rises with age (highest at 75.4% among 74-75
yrs old)
• Rural (33.5%) higher than Urban (29.3%)
Hypertension
• Persistently high arterial blood pressure, defined
as systolic blood pressure above 140 mm Hg
and/or diastolic blood pressure above 90 mm
Hg

• Hypertension is an independent risk factor for


both CHD and stroke

• Hypertension frequently coexists with other


cardiovascular risk factors, including obesity,
dyslipidemia, insulin resistance ,and glucose
intolerance.
Classification Pressure for Adults Ages
18 Years and Older of Blood
Risk Factors for Developing
Hypertension

• Aging
• Genetics (Family history)
• Obesity
• Ethnicity – African American, South Asians
• Salt intake
• High alcohol consumption
Treatment of Hypertension
• Diet and lifestyle changes should be the first
line of therapy for hypertension. (JNC 7 report,
2003)

• Medication : Beta-Blockers, ACE inhibitors –


interferes with conversion of angiotensin I to II,
Diuretics – blood volume
Lifestyle modification
DASH Diet
• Works within 14 days
• Lowers BP quite well
• Includes more potassium, calcium,
other nutrients
DASH Diet

• Pattern
—7-8 whole grains
—4-5 vegetables
—4-5 fruits
—2-3 low-fat or fat-free dairy products
—6 oz or less meat/poultry/fish
—4-5 servings nuts, beans, or legumes/week
—2-3 servings fat (total kcal = 27% fat)
Salt Content & Substitutes
• Composition: KCl, CaCl, Al-Cl
• KCl can provide extra potassium for those taking
diuretics
• KCl can be harmful if patient has renal insufficiency
• “Lite” salt contains sodium
• Some spices and herbs are low in sodium
• Foods that contribute the most sodium to the diet
are canned, smoked, and processed foods, including
frozen and prepared dinners, deli meats, and fast
food
Reduction of Sodium
• Avoid fast foods
• High sodium = pickled, cured, soy sauce, broth
• Fresh, unprocessed foods
• Avoid snack foods, processed meat, processed
fish, tomato based products, canned soups,
cheese, bakery products, sauces
• Use more spices and herbs
Lifestyle Modifications for Prevention
of Hypertension
Risk Factors for Atherosclerosis
• Etiology - risk factors; additive effect
▫ Family history
▫ Age and sex
▫ Obesity
▫ Dyslipidemia
▫ Hypertension
• Etiology - risk factors cont.
▫ Physical inactivity
▫ Atherogenic diet (↑ SF, ↓ fiber)
▫ Diabetes mellitus
▫ Impaired fasting glucose/ metabolic syndrome
▫ Cigarette smoke
Blood lipid levels
Easy memory tips:
Process
• Pathophysiology
▫ Inflammatory response
▫ Injury to endothelial lining
▫ Attracts platelets
▫ Form small clots – thrombi
▫ Continued migration of cells to the area
▫ Proliferation of the plaque
DIETARY FACTORS
Treatment
• Nutrition Therapy
▫ Therapeutic Lifestyle Changes (TLC) developed
as component of ATP-III
 Modifications in fat, cholesterol
 Rich in fruits, vegetables, grains, fiber (↓ LDL)
 Limit sodium to 2400 mg
 Include plant stanols - natural components of
plants which compete with dietary and biliary
cholesterol for absorption in the intestinal
lumen. Recommendation: 2g/day to significantly
reduce LDL levels.
• Nutrition Therapy - Fat Modifications

▫ Total fat 25-35% of calories


▫ Very-low-fat diets
▫ Saturated fat < 7% of calories
▫ Avoid trans fats
▫ Increase intake of monounsaturated fats &
Polyunsaturated omega-6 fatty acids
▫ Increase intake of omega-3 essential fatty acids
▫ Limit dietary cholesterol < 200 mg daily
Management of CVD diseases is optimal with
changes in the diet and lifestyle habits.

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