Cardiovascular Disease
Cardiovascular Disease
• Aging
• Genetics (Family history)
• Obesity
• Ethnicity – African American, South Asians
• Salt intake
• High alcohol consumption
Treatment of Hypertension
• Diet and lifestyle changes should be the first
line of therapy for hypertension. (JNC 7 report,
2003)
• Pattern
—7-8 whole grains
—4-5 vegetables
—4-5 fruits
—2-3 low-fat or fat-free dairy products
—6 oz or less meat/poultry/fish
—4-5 servings nuts, beans, or legumes/week
—2-3 servings fat (total kcal = 27% fat)
Salt Content & Substitutes
• Composition: KCl, CaCl, Al-Cl
• KCl can provide extra potassium for those taking
diuretics
• KCl can be harmful if patient has renal insufficiency
• “Lite” salt contains sodium
• Some spices and herbs are low in sodium
• Foods that contribute the most sodium to the diet
are canned, smoked, and processed foods, including
frozen and prepared dinners, deli meats, and fast
food
Reduction of Sodium
• Avoid fast foods
• High sodium = pickled, cured, soy sauce, broth
• Fresh, unprocessed foods
• Avoid snack foods, processed meat, processed
fish, tomato based products, canned soups,
cheese, bakery products, sauces
• Use more spices and herbs
Lifestyle Modifications for Prevention
of Hypertension
Risk Factors for Atherosclerosis
• Etiology - risk factors; additive effect
▫ Family history
▫ Age and sex
▫ Obesity
▫ Dyslipidemia
▫ Hypertension
• Etiology - risk factors cont.
▫ Physical inactivity
▫ Atherogenic diet (↑ SF, ↓ fiber)
▫ Diabetes mellitus
▫ Impaired fasting glucose/ metabolic syndrome
▫ Cigarette smoke
Blood lipid levels
Easy memory tips:
Process
• Pathophysiology
▫ Inflammatory response
▫ Injury to endothelial lining
▫ Attracts platelets
▫ Form small clots – thrombi
▫ Continued migration of cells to the area
▫ Proliferation of the plaque
DIETARY FACTORS
Treatment
• Nutrition Therapy
▫ Therapeutic Lifestyle Changes (TLC) developed
as component of ATP-III
Modifications in fat, cholesterol
Rich in fruits, vegetables, grains, fiber (↓ LDL)
Limit sodium to 2400 mg
Include plant stanols - natural components of
plants which compete with dietary and biliary
cholesterol for absorption in the intestinal
lumen. Recommendation: 2g/day to significantly
reduce LDL levels.
• Nutrition Therapy - Fat Modifications