1 New Hand Out Detect Pharmaceutical Health&hazards levelII
1 New Hand Out Detect Pharmaceutical Health&hazards levelII
This learning guide is developed to provide you the necessary information regarding the following content
coverage and topics –
● Defining health, safety, welfare and hazard
● Elements of the work environment
● Classification of OHS in pharmacy services
● Financial and social implications of an unsafe workplace
● Methods for identifying OHS
● Women: who make up a large proportion of the work force in many developing countries and often
● Children: who account for a significant part of the work force in many developing countries of ten
under take some of the most hazardous work.
● Migrants: both within countries and between countries who, for a variety of reasons face significant
health and safety hazards at work.
The work environment can be further classified in to physical, chemical and biological and psycho-social
environment. The worker interact with all these environmental agents.
● Physical environment: the physical environment includes; machines, levels of noise, levels of heat and
humidity, levels of dust, vibration, electricity or lighting, radiation etc.
● Chemical environment: the chemical environment includes; chemical dust, mists, fumes, liquids,
vapors etc.
● Biological environment: the biological environment includes; presence of insects and rodents,
microorganisms, poisonous plants and animals.
● Psycho-social environment: Therearenumerouspsycho-
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DETECT PHARMACEUTICAL HEALTH HAZARDS AND ACT HAND OUT FOR PHARMACY TVET STUDENTS
socialfactors,whichoperateatworkplace.Thesearethehumanrelationshipsamongworkers themselves and
those in authorities over them. Examples of psycho-social factors include:- type of work, work
stability, service conditions, job satisfaction, leadership style, security, workers` participation and
communication, motivation and incentives.
The occupational environment of the worker cannot be considered a part from his domestic environment .Both
are complementary to each other. The worker takes his worries to his/her home and bring to his work
disturbances that’s arisen in his/her home .Stress at work may disturb his sleep, just as stress at home may affect
his work.
Physical hazard has possible cumulative or immediate effects on the health of employees. Physical hazard
include: extremes of temperature, ionizing radiation, non-ionizing radiation, excessive noise.
The work environment is either comfortable or extremely cold or hot and uncomfortable. The common physical
hazard in most industries is heat.
Heat Stress
Heat stress is a common problem because people in general function only in a very narrow temperature range.
When fluctuation in core body temperature happens the body attempt to counteract by:
● The capillaries in the skin dilate to bring more blood to the surface so that the rate of cooling is
increased.
Heat stroke
Heat stroke is caused when the body temperature rises rapidly in a worker who is exposed to a work
environment in which the body is unable to cool itself sufficiently. Predisposing factors for heat stroke is
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DETECT PHARMACEUTICAL HEALTH HAZARDS AND ACT HAND OUT FOR PHARMACY TVET STUDENTS
excessive physical exertion in extreme heat condition.
Heat Cramp
Heat cramp is caused exposure to high temperature for a relatively long time particularly if accompanied by
heavy exertion or sweating with excessive loss of salt and moisture.
Heat Exhaustion
This also results from physical exertion in hot environment. Signs of the problem include:
● Weak pulse
● Dizziness
Radiation is a form of energy Any electromagnetic or particulate radiation capable of producing ions is referred
to as ionizing radiation. Radioactive materials emit energy that can damage living tissues.
Electromagnetic
● X-ray
● Gamma ray
Particles
● Alpha radiation
● Beta-rays
● Materials that could be hazardous even when they are located some distance away from the body
(external)
● Materials that are hazardous only when they get inside the body by through breathing, eating or through
broken skin (internal)
This is a form of electromagnetic radiation with varying effect son the exposed body depending largely on the
particular wavelength of the radiation in evolved It includes:-
● Radio transmitters
● TV
● Power line
● Microwaves
● Lasers etc.
Noise is defined as unwanted sound. Sound is any pressure variation or a stimulus that produces a sensory
response in the brain The compression and expansion of air created when an object vibrates.
● Continuous noise :Noise of approximately constant level and spectrum to which an employee is
exposed for a period of eight hours per day or40 hours a week.
● Intermit tent Noise :Exposure to a given sound pressure level several times during a normal working
day
● Auditory effects: involves damage to the structure of the hearing organ which may result permanent or
temporary hearing loss.
The mechanical hazards in industries are contributed from machinery, protruding and moving parts. About 10%
of accidents in industry are said to be due to mechanical causes.
The chemical hazards are on increase with the introduction of newer and complex chemicals. Chemical hazards
form the most important group and comprise over 12000 toxic materials. Such materials may endanger life,
affect health adversely, or cause severe discomfort due to their acute effect. Moreover, they may produce long-
term disease such as cancer.
Naturally occurring materials such as lead and mercury have been recognized as source of occupational disease
for hundreds of years. Other minerals like asbestos, radioactive ores, and oil, are also sources of occupational
disease. Growing range of manmade materials such as plastics, synthetic fibers, solvents, fertilizers, and
pharmaceutical products all of which may be hazardous to those who make or use them.
The physical state of a chemical compound is important in determining its toxicity to man and the environment.
The effects of chemical agents are as follows:
● Asphyxiation
● Systemic intoxication
● Pneumoconiosis
● Carcinogens
● Irritation
Among all chemical agents in work place, the most hazardous and most in contact with the skin or respiratory
system is:
3.3.1. Solvent
In most occupational settings or industries a potential threat to the health, productivity and efficiency of workers
is their exposure to organic solvents. Solvents can cause adverse health effect or fire and explosion.
Aqueous system has low vapor pressure thus the potential hazard by inhalation and subsequent systemic toxicity
is not high.
Examples of aqueous system are: aqueous solution of acids , aqueous solution of alkalis , aqueous solution of
detergents.
Many dangerous substances are used in industry, commerce, agriculture, research activities, hospitals and
teaching establishments.
Corrosive
● Hazard: living tissue as well as equipment are destroyed on contact with this chemicals.
● Caution: Do not breathe vapors and avoid contact with skin eyes, and clothing
Oxidizing
● Hazard: ignite combustible material or worsen existing fire and thus make fire fighting more difficult.
● Caution: Keep away from combustible material. No open cigarette fire allowed in that area.
Harmful
● Hazard: Inhalation and insertion of or skin penetration by these substances is harmful to heath.
● Caution: Avoid contact with the human body, including inhalation of vapors and in cases of malaise
consult doctor.
● Hazard: The substances are very hazardous to health whether breathed, swallowed or in contact with
the skin and may even lead to death.
● Caution: Avoid contact with human body, and immediately consult a doctor in case of malaise.
Irritant
● Hazard: May have an irritant effect on skin, eyes and respiratory organs
● Caution: Do not breathe vapors and avoid contact with skin and eye
Highly Flammable
Explosive
Exposure to biological hazards in work place results in a significant amount of occupationally associated
infections. Biological hazards in clued viruses ,bacteria, fungus ,parasites or any living organism that can cause
disease to human beings.
● Inhalation
● Injection
● Ingestion
Laboratory
Health personnel such as Laboratory technicians and scientists working on biological specimens are at risk with
biological hazards in the laboratory Specimen such as blood ,pus ,stool and other tissue samples may expose the
workers to hazards such as HIV, Hepatitis, etc.
Hospitals
Many potential biological agent sex is tin hospital environment. These are bacterial infection and viral
agents .Those working in laundry, housekeeping, laboratory, central supply and nursing station are highly
exposed to bio hazard from the patient they handle ,from the specimen they collect and from the cloth needle
and pans they handle and from their general day to day activities.
Agriculture
Occupational exposures to bio hazard also occurring agriculture. Disease of vertebrate animals transmissible to
human and other animals (Zoonosis). Zoonotic diseases
consistsofviral,bacterial,rickettsial,fungal,protozoal,andhelminthic disease.
Ergonomicsistheapplicationofhumanbiologicalscienceinconjunctionwiththeengineeringscienceinordertoachieveo
ptimum mutual adjustment of man and his work.
Ergonomics deals with the interaction between humans and environmental elements such as heat ,light,
sound ,atmospheric contaminants and all tools and equipment pertaining to the work place.
Ergonomics or the proper designing of work systems based on human factors has the following
advantages:
The goal of Ergonomics ranges from making work safe to humans ,and increasing human efficiency and well-
being
The terms tress means the strain imposed on the worker by psycho-social influences associated with works,
whichmayaffecthealth,wellbeing,andproductivity.Reductionofoccupationalstressesdependsnotonlyonhelping
individuals to cope with their problems but also on:
● Good management
Unsafe workplace do not only cause terrible human tragedies but also substantial social and economic impacts
on society. The social impact could be defined as the effect that touches the human side of the society, where the
economic impact could be defined as the effect that relates to the financial aspects of the society. All society
Economic impacts of workplace accidents on the affected individual and family are
● Decrease income
From a business standpoint, workplace accidents affect the profitability of a business. Economic impacts of
unsafe workplace could have direct and indirect costs. A direct cost is defined as those costs covered by the
workers compensation insurance. These may include medical costs, premiums for workers, compensation
insurance, liability and property losses. Indirect costs are those costs attributed to loss of productivity of the
injured worker.
● Loss of productivity
● Medical payments
Unsafe workplaces have social impacts on the worker, his/her family, employer and community as a whole.
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DETECT PHARMACEUTICAL HEALTH HAZARDS AND ACT HAND OUT FOR PHARMACY TVET STUDENTS
Serious workplaces accident has the potential to induce a crisis within an organization. The employees go
through a state of shock, loss and regret and in some instances guilt. During this period, psychological stress and
tension grow and the organization will become consumed with accusation and blame and that the energies may
be diverted away from the tasks at hand.
● Family depression
● Degradation of morale
Hazards generally arise from the following aspects of work and their interaction.
Some hazards are part of the work process, such as mechanical hazards, noise or toxic properties of substances.
Other hazards result from equipment or machine failures and misuse, chemical spills and structural failures.
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Machines, equipment, substance or a work process may have many different hazards. Each of these hazards
needs to be identified.
Gravity Falling objects, falls, slips and trips of people can cause
fractures, bruises, lacerations, dislocations, concussion,
permanent injuries or death
Machinery and equipment Being hit by moving vehicles, or caught by moving parts of
machinery can cause fractures, bruises, lacerations,
dislocations, permanent injuries or death
hearing damage
Regularly walking around the workplace and observing how things are done can help us to predict what could or
might go wrong. Look at how people actually work, how machines and equipment is used, what chemicals are
around and what they are used for, what safe or unsafe work practices exist as well as the general state of
housekeeping.
● Does the work environment enable workers to carry out work without risks to health and safety (for
example, space for unobstructed movement, adequate ventilation, lighting)?
● How suitable are the tools and equipment for the task and how well are they maintained?
● Have any changes occurred in the workplace which may affect health and safety?
● Some hazards can affect health over a long period of time or may result in stress (such as bullying) or
fatigue.
● If you find a situation where there is immediate or significant danger to people, move those persons to a
safer location first and attend to the hazard urgently.
Make a list of all the hazards you can find to ensure that nothing is missed. You may use a checklist designed to
suit your workplace to help you find and make a note of hazards.
Ask workers about any health and safety problems they have encountered in doing their work and any near
misses or incidents that have not been reported.
Worker surveys may also be undertaken to obtain information about matters such as workplace bullying, as well
as muscular aches and pains that can signal potential hazards.
Information and advice about hazards and risks relevant to particular industries and types of work is available
from regulators, technical specialists and safety consultants.
Analyze all records of health monitoring, workplace incidents, worker complaints, sick leave and the results of
any inspections and investigations to identify hazards. If someone has been hurt doing a particular task, then a
hazard exists that could hurt someone else. These incidents need to be investigated to find the hazard that caused
the injury or illness.
Evaluation can be defined as the decision making process that results in an opinion as to the degree of risk
arising from exposure to chemical, physical, biological, or other agents. It also involves making a judgment of
the magnitude of these agents and determines the levels of contaminants arising from a process or work
operation and the effectiveness of any control measures used.
Evaluation Methods
Environmental sampling includes sampling for gases, vapors, aerosol concentrations, noise, temperature etc.
Which are found on the worker or the general work area or environment.
Area or general room air samplings are taken at fixed locations in the work place. This type of sampling does
not provide a good estimate of worker exposure. For this reason it is used mainly to pinpoint high exposure
areas, indicate flammable or explosive concentrations, or determine if an area should be isolated or restricted to
prevent employees from entering a highly contaminated area.
Personal sampling
The objective of personal sampling is to see the extent of exposure of the person working on a particular
contaminant while he/she is working at a location or work place. For example, if the worker is working in a
garage where cars are painted, the area as a whole is sampled to see how much lead which is present in all car
paints. In addition, personal sampling ill be taken to determine how much lead is inhaled by the person
Dust evaluation
To evaluate dust exposure, it is first necessary to determine the composition of dust that are suspended in the air
where workers breathe. Operation that involves the crushing, grinding, or polishing of minerals or mineral
mixtures frequently do not produce airborne dusts that have the same size composition.
When air samples are collected in the immediate vicinity of dust producing operation, larger particles that have
not yet had time to settle from the air may be collected. If a larger number of these particles appear in the dust
sample, the effect of their presence may have to be evaluated separately. To evaluate either the relative hazard to
health posed by dusts or effectiveness of dust control measures, one must have a method of determining the
extent of the dust problem.
Air contamination can be divided into two broad groups depending upon physical characteristics.
● Particulate
The type of air sampling to be used depends upon a number of factors such as; the type of sampling, the
equipment available, the environmental condition and the nature of the toxic contaminants
Noise Evaluation
● To obtain specific information on the noise levels existing at each employee Workstation
Medicines which are unfit for use should be disposed properly after getting approval from the
appropriate organ.
Any medicines waste disposal practice, including diluting and flushing of liquid medicines into sewers
and burning of packaging materials, should be attended by an inspector of the appropriate organ.
After disposal of medicines waste have been carried out, disposal certificates will be issued by the
appropriate organ
Disposal sites should be environment and society friendly and be approved by appropriate organ in
accordance with Environment Impact Assessment (EIA). The disposal site must be safe in order to
prevent re-use of any medicines waste including re-packing and re-labeling. In addition, security
measures to prevent scavenging must be in place at disposal sites and temporary storage areas.
Organizations which does not have an approved disposal facility may use disposal referral system of
licensed disposal firms, medicines suppliers or central disposal sites.
The disposal of medicines waste must be carried out according to the sorting procedures and
recommended disposal methods by the appropriate organ.
All workers who are involved in a disposal process must wear appropriate personal protective equipment
such as gowns, boots, gloves, safety glasses/goggles, masks, and caps.
Each medicine waste must be recorded on the register book. Special emphasis should be given to
segregate and store controlled drugs or substances, anti-neoplastic or cytotoxic/anti–cancer medicines,
anti-infective medicines, radiopharmaceuticals and any other hazardous products like antiseptics and
disinfectants until their separate and safe disposal.
Medicine wastes other than mentioned above can be categorized and kept by dosage
forms:
● Solids, semi-solids and powders: tablets, capsules, granules, powders for injection, mixtures, lotions,
creams, gels, suppositories etc.,
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● Liquids: solutions, suspension, syrups, ampoules etc.
Waste paper and packing materials may be sorted and recycled (if facilities are available), burned or disposed of
as normal waste to a landfill. Plastic, metal and glass items may be reused, recycled or disposed of in a landfill.
Depending on the type of material and the purpose of reuse, appropriate treatment such as cleaning or
disinfecting of reusable materials may be needed.
Containers must be kept according to dosage forms to facilitate verification, sorting and selection of disposal
methods. An area or room for keeping containers of medicines waste must be demarcated and labeled
conspicuously with words “Expired medicines–Not for Sale” or “Unfit medicines–Not for sale” in red ink.