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DRUG SUFFIXES CHEAT SHEET

– SORTED BY DRUG TYPE – 1

A suffix is the ending of a word, placed after the word’s stem, which often communicates meaning. Drug suffixes
are commonly used to group drugs based on the drug’s action.

BLOOD PRESSURE MEDICATIONS

Drug Classification Suffix Examples Action

captopril Reduce blood pressure by dilating blood


ACE Inhibitors -pril vessels, thus reducing the heart’s workload.
lisinopril

atenolol Reduce blood pressure by slowing the heart


rate and reducing myocardial contractility.
Beta Blockers -lol metoprolol
They are most often given for hypertension
propranolol and chronic heart failure.

Relax blood vessels, therefore increasing


amlodipine blood supply and oxygen to the heart and
Calcium Channel Blockers -dipine
nifedipine reducing the heart’s workload while
lowering blood pressure.

Angiotensin-II losartan Inhibit blood vessel constriction, helping


-sartan blood vessels relax, which lowers blood
Receptor Blockers valsartan pressure.

ADDITIONAL CARDIOVASCULAR MEDICATIONS

Drug Classification Suffix Examples Action


Increase the fluid excreted by the kidneys,
spironolactone while retaining potassium in the body.
Potassium-Sparing Diuretics -actone reduces cardiovascular congestion and
aldactone edema that results from CHF. They also
lower blood pressure.

Increase fluid and potassium excreted by


the kidneys. Reduces cardiovascular
Thiazide Diuretics -thiazide hydrochlorothiazide congestion and edema that results from
CHF. They also lower blood pressure.

atorvastatin Reduce LDL cholesterol and lower risks from


Antilipidemics -statin
simvastatin cardiovascular disease.

“Clot busters” that break down clots that


streptokinase
Thrombolytics -ase lead to heart attacks or strokes, to restore
alteplase (tPA) blood flow to the obstructed area.

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DRUG SUFFIXES CHEAT SHEET
– SORTED BY DRUG TYPE – 2

ANTIBIOTIC MEDICATIONS

Drug Classification Suffix Examples Action


tetracycline
Tetracyclines -cycline
doxycycline

-mycin gentamicin Broad spectrum antibiotics that treat


Aminoglycosides
-micin tobramycin bacterial infections.

ciprofloxacin
Fluoroquinolones -floxacin
levofloxacin

GASTROINTESTINAL MEDICATIONS

Drug Classification Suffix Examples Action

Antiemetics -azine promethazine Treat and prevent nausea and vomiting.

lansoprazole Anti-ulcer drugs that reduce gastric acid


Proton Pump Inhibitors -prazole production.
omeprazole

H2-receptor Antagonists cimetidine Block the action of histamine in the stomach,


-tidine
(H2 Blockers) famotidine decreasing the production of stomach acid.

RESPIRATORY MEDICATIONS

Drug Classification Suffix Examples Action

albuterol Dilate the bronchi and bronchioles,


-terol decreasing resistance in the airway and
Bronchodilators levabuterol
-phylline increasing airflow to the lungs. Often used
theophylline for asthma and COPD.

diphenhydramine Treat allergy symptoms, such as sneezing,


Antihistamines -ine loratadine runny nose, itching, and hives, caused by
brompheniramine histamine activation.

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DRUG SUFFIXES CHEAT SHEET
– SORTED BY DRUG TYPE – 3

DEPRESSION AND ANXIETY MEDICATIONS

Drug Classification Suffix Examples Action


alprazolam Treat anxiety; prolonged use may lead to
-pam physical dependence.
Benzodiazepines diazepam
-lam
lorazepam

amitriptyline Treat depression, bipolar disorder, anxiety,


Tricyclic Antidepressants -triptyline OCD, and other mood disorders.
nortriptyline

Selective Serotonin fluoxetine Block or delay the reabsorption of serotonin;


-pram
Reuptake Inhibitors sertraline used to treat major depressive disorders and
-ine anxiety disorders
(SSRIs) citalopram

ADDITIONAL MEDICATIONS

Drug Classification Suffix Examples Action

lidocaine Prevent the transmission of nerve impulses


Local Anesthetics -caine
xylocaine or pain without causing unconsciousness.

dexamethasone Anti-inflammatory drugs used to control


-sone
Corticosteroids prednisone many different inflammation-related
-lone
methylprednisolone symptoms.

Meglitinides repaglinide Lower blood glucose levels by triggering the


nateglinide production of insulin; used to treat type 2
-ide diabetes.
glyburide
Sulfonylureas glipizide

NOTES:

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