Pharmacology Midterm
Pharmacology Midterm
Pharmacology Midterm
1. A nurse is caring for a 4-year-old child who is resistant to taking medication. Which of
the following strategies should the nurse use to elicit the child’s cooperation?
a. Offer the child a choice of taking the medication with juice or water
b. Tell the child it is candy
c. Hide the medications in a large dish of ice cream
d. Tell the child he will have a shot instead
2. A nurse is caring for a client who has difficulty swallowing medications and is prescribed
enteric-coated aspirin PO once daily. The client asks if the medication can be crushed to
make it easier to swallow. Which of the following responses should the nurse provide?
a. "Crushing the medication might cause you to have a stomachache or indigestion.
i. Rationale: The pill is enteric-coated to prevent breakdown in the stomach
and decrease the possibility of GI distress. Crushing destroys protection.
b. "Crushing the medication is a good idea, and I can mix it in some ice cream for
you.”
c. "Crushing the medication would release all the medication at once, rather than
over time."
d. "Crushing is unsafe, as it destroys the ingredients in the medication."
3. A nurse is caring for a client who has congestive heart failure and is taking digoxin daily.
The client refused breakfast and is complaining of nausea and weakness. Which of the
following actions should the nurse take first?
a. A. Check the client's vital signs.
i. Rationale: It is possible that the client's nausea is secondary to digoxin
toxicity. Assess for bradycardia, a symptom of digoxin toxicity. The nurse
should withhold the medication and call the provider if the client's heart
rate is less than 60 bpm.
b. Request a dietitian consult.
c. Suggest that the client rests before eating the meal.
d. Request an order for an antiemetic.
4. A nurse is caring for a client who has thrombophlebitis and is receiving heparin by
continuous IV infusion. The client asks the nurse how long it will take for the heparin to
dissolve the clot. Which of the following responses should the nurse give?
a. "It usually takes heparin at least 2 to 3 days to reach a therapeutic blood level."
b. "A pharmacist is the person to answer that question."
c. "Heparin does not dissolve clots. It stops new clots from forming."
i. Rationale: This statement accurately answers the client's question.
d. "The oral medication you will take after this IV will dissolve the clot.
5. A nurse is caring for a client who has bipolar disorder and has been taking lithium for 1
year. Before administering the medication, the nurse should check to see that which of the
following tests have been completed?
a. Thyroid hormone assay
i. Rationale: Thyroid testing is important because long-term use of lithium
may lead to thyroid dysfunction.
b. Liver function tests:
i. Rationale: LFTs must be monitored before and during valproic acid
therapy
c. Erythrocyte sedimentation rate
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Pharmacology Midterm
i. Rationale: This is not a necessary test related to lithium therapy.
d. Brain natriuretic peptide
6. A nurse is providing discharge teaching to a client who has asthma and new prescriptions
for cromolyn and albuterol, both by nebulizer. Which of the following statements by the
client indicates an understanding of the teaching?
a. “If my breathing begins to feel tight, I will use the cromolyn immediately.”
b. “I will be sure to take the albuterol before taking the cromolyn.”
i. Rationale: The client should always use the bronchodilator (albuterol)
prior to using the leukotriene modifier (cromolyn). Using the
bronchodilator first allows the airways to be opened, ensuring that the
maximum dose of medication will get to the client's lungs.
c. “I will use both medications immediately after exercising.”
d. “I will administer the medications 10 minutes apart.”
7. A nurse is completing a medication history for a client who reports using over-the-
counter calcium carbonate antacid. Which of the following recommendations should the
nurse make about taking this medication?
a. Decrease bulk in the diet to counteract the adverse effect of diarrhea.
b. Take the medication with dairy products to increase absorption.
c. Reduce sodium intake.
d. Drink a glass of water after taking the medication.
i. Calcium carbonate is a dietary supplement used when the amount of
calcium taken in the diet is not enough. Calcium carbonate may also be
used as an antacid to relieve heartburn, acid indigestion, and stomach
upset. The client should drink a full glass of water after taking an antacid
to enhance its effectiveness.
8. A nurse is caring for a client who has deep vein thrombosis and has been on heparin
continuous infusion for 5 days. The provider prescribes warfarin PO without
discontinuing the heparin. The client asks the nurse why both anticoagulants are
necessary. Which of the following statements should the nurse make?
a. "Warfarin takes several days to work, so the IV heparin will be used until the
warfarin reaches a therapeutic level."
i. Rationale: However, these medications work in different ways to achieve
therapeutic coagulation and must be given together until therapeutic levels
of anticoagulation can be achieved by warfarin alone, which is usually
within 1 to 5 days. When the client's PT and INR are within therapeutic
range, the heparin can be discontinued.
b. "I will call the provider to get a prescription for discontinuing the IV heparin
today.”
c. "Both heparin and warfarin work together to dissolve the clots."
d. "The IV heparin increases the effects of the warfarin and decreases the length of
your hospital stay."
9. A nurse is providing teaching to a client who has asthma and a new prescription for
inhaled beclomethasone. Which of the following instructions should the nurse provide?
a. Check the pulse after medication administration.
b. Take the medication with meals.
c. C. Rinse the mouth after administration.
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Pharmacology Midterm
i. Rationale: Use of glucocorticoids by metered dose inhaler can allow a
fungal overgrowth in the mouth. Rinsing the mouth after administration
can lessen the likelihood of this complication.
d. Limit caffeine intake.
10. A nurse is teaching a client who has a new prescription for colchicine to treat gout. Which
of the following instructions should the nurse include?
a. "Take this medication with food if nausea develops."
b. B. "Monitor for muscle pain."
i. Rationale: This medication can cause rhabdomyolysis. The client should
monitor and report muscle pain.
c. "Expect to have increased bruising."
d. "Increase your intake of grapefruit juice”
11. A nurse is caring for a client who has active pulmonary tuberculosis (TB) and is to be
started on intravenous rifampin therapy. The nurse should instruct the client that this
medication can cause which of the following adverse effects?
a. Constipation
c. Staining of teeth
12. A nurse caring for a client who has hypertension and asks the nurse about a prescription
for propranolol. The nurse should inform the client that this medication is contraindicated
in clients who have a history of which of the following conditions?
a) Asthma
b) Glaucoma
c) Depression
d) Migraines
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Pharmacology Midterm
13. A nurse is teaching a client who has chronic kidney disease and a new prescription for
epoetin alfa. The nurse should instruct the client to increase dietary intake of which of the
following substances?
a. Iron
b. Protein
c. Potassium
d. Sodium
14. A nurse is assessing a client who is receiving IV vancomycin. The nurse notes a flushing
of the neck and tachycardia. Which of the following actions should the nurse take?
15. A nurse is teaching a client who has a urinary tract infection (UTI) and is taking
ciprofloxacin. Which of the following instructions should the nurse give to the client?
a. "If the medicine causes an upset stomach, take an antacid at the same time."
d. "You should report any tendon discomfort you experience while taking this
medication."
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Pharmacology Midterm
i. Rationale: The nurse should instruct the client to report any tendon
discomfort as well as swelling or inflammation of the tendons due to the
risk of tendon rupture.
16. A nurse is preparing to administer verapamil by IV bolus to a client who is having cardiac
dysrhythmias. For which of the following adverse effects should the nurse monitor when
giving this medication?
a. Hyperthermia
b. Hypotension
c. Ototoxicity
d. Muscle pain
17. A nurse is caring for a client who has a fungal infection and has a new prescription for
amphotericin B. Which of the following laboratory values should the nurse report to the
provider before initiating the medication?
a. Sodium 140 mEq/L
b. Potassium 4.5 mEq/L
c. BUN 55 mg/dL
i. Rationale: This BUN level is above the expected reference range (10-20
mg/dL). Amphotericin B is nephrotoxic and is contraindicated if BUN is >
40mg/dL.
d. D. Glucose 120 mg/dL
e. Glucose 120 mg/dL
18. A nurse is providing teaching to a client who has renal failure and an elevated
phosphorous level. The provider instructed the client to take aluminum hydroxide 300 mg
PO three times daily. For which of the following adverse effects should the nurse inform
the client?
a. Constipation
i. Rationale: Constipation is a common side effect of aluminum-based
antacids. The nurse should instruct the client to increase fiber intake and
that stool softeners or laxatives may be needed
b. B. Metallic taste
c. Headache
d. Muscle spasms
19. A nurse is teaching a client who has been taking prednisone to treat asthma and has a new
prescription to discontinue the medication. The nurse should explain to the client to
reduce the dose gradually to prevent which of the following adverse effects?
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Pharmacology Midterm
a. Hyperglycemia
b. Adrenocortical insufficiency
Rationale: Prednisone, a corticosteroid, is similar to cortisol, the glucocorticoid
hormone produced by the adrenal glands. It relieves inflammation and is used to
treat certain forms of arthritis, severe allergies, autoimmune disorders, and
asthma. Administration of glucocorticoids can suppress production of
glucocorticoids, and an abrupt withdrawal of the drug can lead to a syndrome of
adrenal insufficiency.
c. Severe dehydration
d. Rebound pulmonary congestion
20. A nurse is preparing a client for surgery. Prior to administering the prescribed
hydroxyzine, the nurse should explain to the client that the medication is for which of the
following indications? (Select all that apply.)
a. Controlling emesis
b. Diminishing anxiety
c. Reducing the amount of narcotics needed for pain relief
d. Preventing thrombus formation
e. Drying secretions
21. A nurse is caring for a client who has streptococcal pneumonia and a prescription for
penicillin G by intermittent IV bolus. 10 minutes into the infusion of the third dose, the
client reports that the IV site itches and that he feels dizzy and short of breath. Which of
the following actions should the nurse take first?
a. Stop the infusion.
i. Rationale: When using the airway, breathing, circulation approach to
client care, the nurse should place the priority on stopping the infusion.
The client is exhibiting signs of penicillin anaphylaxis and the first action
that should be taken is to withdraw the medication.
b. Call the client's provider.
c. Elevate the head of the bed.
d. Auscultate the client's breath sounds.
22. A nurse is caring for a client who is taking lisinopril. Which of the following outcomes
indicates a therapeutic effect of the medication?
a. Decreased blood pressure
i. Rationale: Lisinopril, an ACE inhibitor, may be used alone or in
combination with other antihypertensives in the management of
hypertension and congestive heart failure. A therapeutic effect of the
medication is a decrease in blood pressure.
b. Increase of HDL cholesterol
c. Prevention of bipolar manic episodes
d. Improved sexual function
23. A nurse is caring for a client who has poison ivy and is prescribed diphenhydramine.
Which of the following instructions should the nurse give regarding the adverse effect of
dry mouth associated with diphenhydramine?
a. "Administer the medication with food."
b. "Chew on sugarless gum or suck on hard, sour candies."
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Pharmacology Midterm
i. Rationale: Clients who report dry mouth can get the most effective relief
by sucking on hard candies (especially the sour varieties that stimulate
salivation), chewing gum, or rinsing the mouth frequently. It is the local
effect of these actions that provides comfort to the client.
c. "Place a humidifier at your bedside every evening."
d. “discontinue the medication and notify your provider”
24. A nurse is caring for a client who has an infection and a prescription for gentamicin
intermittent IV bolus every 8 hr. A peak and trough is required with the next dose. Which
of the following actions should the nurse take to obtain an accurate gentamicin serum
level?
a. Draw a trough level at 0900 and a peak level at 2100.
b. Draw a peak level 90 min prior to administering the medication and a trough level
90 min after the dose.
c. Draw a trough level immediately prior to administering the medication and a peak
level 30 min after the dose.
i. Rationale: Timing of the peak and trough is based on the
pharmacokinetics of absorption and the half-life of the medication. The
trough level is the lowest serum level after pharmacokinetic effects have
taken place. For divided doses, correct timing for the trough is just before
administering the next dose. The peak is the highest serum level of the
medication; if this level is too low, then the medication will not be
effective. Correct timing for the peak is between 30 and 60 min after the
dose has finished infusing.
d. Draw a peak level at 0900 and a trough level at 2100.
25. A nurse in a substance abuse clinic is assessing a client who recently started taking
disulfiram. The client reports having discontinued the medication after experiencing
severe nausea and vomiting. Which of the following reasons should the nurse suspect to
be a likely cause of the client's distress?
26. A nurse is reviewing the medical record of a client who has been on levothyroxine for
several months. Which of the following findings indicates a therapeutic response to the
medication?
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Pharmacology Midterm
a. Decrease in level of thyroxine (T4)
b. Increase in weight
27. A nurse on an oncology unit is preparing to administer doxorubicin to a client who has
breast cancer. Prior to beginning the infusion, the nurse verifies the client's current
cumulative lifetime dose of the medication. For which of the following reasons is this
verification necessary?
d. Exceeding the lifetime cumulative dose limit of doxorubicin might produce red
tinged urine and sweat.
28. A nurse is caring for a client who is taking naproxen following an exacerbation of
rheumatoid arthritis. Which of the following statements by the client requires further
discussion by the nurse?
29. A nurse is caring for a client who has heart failure and a prescription for digoxin. Which
of the following statements by the client indicates an adverse effect of the medication?
30. A nurse is providing teaching for a client who has anemia and a new prescription for
ferrous sulfate liquid. Which of the following instructions should the nurse provide?
ii. Rationale: Ascorbic acid (vitamin C), which is found in orange juice, will
enhance the absorption of iron and increase its bioavailability. This will
also help to decrease the gastrointestinal side effects of iron.
31. A nurse is preparing to administer a dose of lactulose to a client who has cirrhosis. The
client states, "I don't need this medication. I am not constipated." The nurse should
explain that in clients who have cirrhosis, lactulose is used to decrease levels of which of
the following components in the bloodstream?
a. Glucose
b. Ammonia
c. Potassium
d. Bicarbonate
32. A nurse is caring for a client who has HIV-1 infection and is prescribed zidovudine as
part of antiretroviral therapy. The nurse should monitor the client for which of the
following adverse effects of this medication?
a. Cardiac dysrhythmia
b. Metabolic alkalosis
c. Renal failure
d. Aplastic anemia
33. A nurse is caring for a client who has chronic renal disease and is receiving therapy with
epoetin alfa. Which of the following laboratory results should the nurse review for an
indication of a therapeutic effect of the medication?
34. A nurse is caring for a client who is prescribed warfarin therapy for an artificial heart
valve. Which of the following laboratory values should the nurse monitor for a
therapeutic effect of warfarin?
a. Hemoglobin
c. Bleeding time
35. A nurse in a critical care unit is caring for a client who is postoperative following a right
pneumonectomy. After extubation from the ventilator, in which of the following positions
should the client be placed?
a. Prone
c. Sims'
d. Semi-Fowler's
36. A nurse in a coronary care unit is admitting a client who has had CPR following a cardiac
arrest. The client is receiving lidocaine IV at 2 mg/min. When the client asks the nurse
why he is receiving that medication, the nurse should explain that it has which of the
following actions?
a. Prevents dysrhythmias
d. Relieves pain
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Pharmacology Midterm
37. A nurse in a provider's clinic is assessing a client who has cancer and a prescription for
methotrexate PO. Which of the following actions should the nurse take when the client
reports bleeding gums?
i. Rationale: The nurse should recognize that the bleeding is likely due to
the adverse effect of the chemotherapy and needs to be evaluated further.
Bleeding gums is a sign of thrombocytopenia (decreased platelet count)
secondary to bone marrow suppression, which can be life-threatening in a
client who is receiving chemotherapy.
38. A nurse is caring for a client who has bipolar disorder and has been taking lithium for 1
year. Before administering the medication, the nurse should check to see that which of the
following tests have been completed?
39. A nurse in a mental health clinic is caring for a client who has bipolar disorder and a
prescription for an antipsychotic medication. The provider and nursing staff suspect the
client is not adhering to his medication therapy. Which of the following interventions
should the staff use to encourage the client's adherence? (Select all that apply.)
Rationale: Perform mouth checks following the administration of medication is incorrect. Mouth
checks may not find pills that the client has hidden in his mouth.Provide for once-daily dosing is
correct. Once-daily dosing of medications simplifies the therapy, making it easier for the client to
comply.Use sustained-release forms is correct. Sustained-release forms remain in the client's
system longer, requiring less frequent dosing.Engage the client in conversation following
medication administration is correct. If the client is speaking, he will be less likely able to hide
the medication in his mouth.Rotate staff that administers the medications is incorrect. Rotating
treatment providers is an obstacle that increases the risk of a client's nonadherence to therapy.
40. A nurse in a provider's clinic is caring for a client who reports erectile dysfunction and
requests a prescription for sildenafil. Which of the following medications currently
prescribed for the client is a contraindication to taking sildenafil?
a. Isosorbide
b. Phenytoin
c. Metronidazole
d. Prednisone
41. A nurse is caring for a client who has developed gout. Which of the following
medications should the nurse prepare to administer?
a. Zolpidem
b. Alprazolam
c. Spironolactone
d. Allopurinol
42. A nurse is caring for a client who has diabetes insipidus and is receiving vasopressin. The
nurse should identify which of the following findings as an indication that the medication
is effective?
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Pharmacology Midterm
a. A decrease in blood sugar
43. A nurse on a medical unit is planning care for an older adult client who takes several
medications. Which of the following prescribed medications places the client at risk for
orthostatic hypotension? (Select all that apply.)
a. Furosemide
b. Telmisartan
c. Duloxetine
d. Clopidogrel
e. Atorvastatin
44. A home health nurse is assessing an older adult client who reports falling a couple of
times over the past week. Which of the following findings should the nurse suspect is
contributing to the client's falls?
45. A nurse is teaching a client who takes warfarin daily. Which of the following statements
by the client indicates a need for further teaching?
i. Rationale: Ginger root can interfere with the blood clotting effect of
warfarin and place the client at risk for bleeding. This statement indicates
the client needs further teaching.
46. A nurse is teaching a client about the adverse effects of cisplatin. Which of the following
adverse effects should the nurse include in the teaching?
a. Tinnitus
b. Constipation
c. Hyperkalemia
d. Weight gain
47. A nurse is completing a medical interview with a client who has elevated cholesterol
levels and takes warfarin. The nurse should recognize that which of the following actions
by the client can potentiate the effects of warfarin?
c. The client sprinkles flax seeds on food 1 hr before taking the anticoagulant.
a. "Taking the medication between meals will help you avoid becoming
constipated."
c. "Taking the medication between meals will help you absorb the medication more
efficiently."
49. A nurse is caring for a female client who has rheumatoid arthritis and asks the nurse if it
is safe for her to take aspirin. The nurse should recognize which of the following findings
in the client's history is a contraindication to this medication?
50. A nurse is providing discharge teaching for a client who has a new prescription for
warfarin. Which of the following instructions should the nurse include in the teaching?
51. A nurse is providing teaching to a client who has emphysema and a new prescription for
theophylline. Which of the following instructions should the nurse provide?
i. Rationale: The nurse should instruct the client that caffeine should be
avoided while taking theophylline, as it can increase central nervous
system stimulation.
52. Nurse is teaching about furosemide, the nurse should recommend what foods about best
source of potassium
a. Bananas
a. Respiratory rate
55. Giving ophthalmic ointment for Conjunctivitis, what instructions do you have
a. Metallic taste
59. 4 clients and you gave all medications, but procardia/nitrate was given to wrong person
what do you do first?
a. Check vitals
a. Grapefruit