Scribd Logo
Upload

Welcome to Scribd!

  • History of Laboratory Biosafety

    Uploaded by

    G
    49 views4 pages
    The history of laboratory biosafety began in the 1940s with the establishment of the US biological weapons program and the tasking of IRA L. Baldwin to develop defenses against such weapons. In the 1940s and 1950s, biosafety was recognized as important for developing biological weapons. Key figures like Arnold Wedum in the 1900s and 1940s pioneered the development of practices, equipment, and facilities to control biological hazards and prevent laboratory infections. International biosafety standards and regulations developed throughout the 1960s-2000s to help regulate dangerous biological agents and protect human health. Various international organizations also formed to help promote best practices in biosafety.

    Original Description:

    Copyright

    © © All Rights Reserved

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    The history of laboratory biosafety began in the 1940s with the establishment of the US biological weapons program and the tasking of IRA L. Baldwin to develop defenses against such weapons. In the 1940s and 1950s, biosafety was recognized as important for developing biological weapons. Key figures like Arnold Wedum in the 1900s and 1940s pioneered the development of practices, equipment, and facilities to control biological hazards and prevent laboratory infections. International biosafety standards and regulations developed throughout the 1960s-2000s to help regulate dangerous biological agents and protect human health. Various international organizations also formed to help promote best practices in biosafety.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    49 views4 pages

    History of Laboratory Biosafety

    Uploaded by

    G
    The history of laboratory biosafety began in the 1940s with the establishment of the US biological weapons program and the tasking of IRA L. Baldwin to develop defenses against such weapons. In the 1940s and 1950s, biosafety was recognized as important for developing biological weapons. Key figures like Arnold Wedum in the 1900s and 1940s pioneered the development of practices, equipment, and facilities to control biological hazards and prevent laboratory infections. International biosafety standards and regulations developed throughout the 1960s-2000s to help regulate dangerous biological agents and protect human health. Various international organizations also formed to help promote best practices in biosafety.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    of 4

    HISTORY OF LABORATORY BIOSAFETY

    1943

    The established of US biological weapons program began.

    IRA L. BALDWIN was tasked in establishing the biological weapons program for defensive purposes to
    enable the US to respond if attacked by such weapons.

    AFTER THE 2ND WORLD WAR

    Biosafety was an inherent component of biological weapons development.


    NEWELL A. JOHNSON

    1984

    The formation of American Biological Safety Association (ABSA)

    1907 and 1908

    ARNOLD WEDUM described the use of mechanical pipettors to prevent laboratory acquired infections.

    Ventilated Cabinets

    1909

    A pharmaceutical company in Pennsylvania developed a ventilated cabinet to prevent infection from


    Mycobacterium Tuberculosis.

    1944

    ARNOLD WEDUM, director of Industrial Health and Safety of the US Army Biological Research
    Laboratories was recognized as one of the pioneers of biosafety that provided the foundation for
    evaluating the risks of handling the infectious microorganisms and for recognizing biological hazards and
    developing practices, equipment and facility safeguards for their control.

    1966

    WEDUM and microbiologist MORTON REITMAN


    Colleague at FORT DETRICK, analyze multiple epidemiological studies at laboratory-based outbreaks.

    1967

    WHO aggressively pursued the eradication of the virus

    It was also during this time that serious concerns about biosafety practices worldwide raised.
    WORLD HEALTH ASSEMBLY

     THE CENTER FOR DISEASE CONTROL AND PREVENTION


     STATE RESEARCH CENTER OF VIROLOGY AND BIOTECHNOLOGY VECTOR

    Variolation

    Named after the virus that causes smallpox (variola virus)

     Variola Major
     Variola Minor

    1974

    CDC published the Classification of Etiological Agents on the Basis of Hazard

    2 years later

    National Institutes of Health of the United States published the NIH Guidelines for Research involving
    the Recombinant DNA molecules.

     Laboratory Biosafety Manual

     Biosafety in Microbiological and Biomedical Laboratories

    Marked the development of the practice of laboratory biosafety

    Document established the model of biosafety containment levels with certain agents which increased
    the biosafety levels for biological agents that pose risk to human health.

    1996

    Us government enacted the SELECT AGENT REGULATIONS to monitor the transfer of a select list at
    biological agents from one facility to another.

    2001

    Amerithrax

    The revival SELECT AGENT REGULATIONS required specific security measures for any facility in the
    United States that used or stored one or more agents or the new longer list of agents.

    PAPER MESSAGE

    09-11-01
    “THIS IS NEXT, TAKE PENACILIN NOW, DEATH TO AMERICA DEATH TO ISRAEL, ALLAH IS GREAT”

    BRUCE IVINS

    One who developed the Anthrax (Bacillus anthracis) vaccine

    2012

    The revision of the SELECT AGENT REGULATIONS sought to address the creation of 2 tiers of select
    agents.

    Tier 1 agents

    Materials that pose the greatest risk of deliberate misuse, and the remaining select agents.

    SELECT AGENTS AND TOXINS

    Tier one Select agents and Toxins examples:

     Bacillus anthracis
     Bacillus cereus
     Clostridium
     Burkholderia pseudomallei
     Ebola virus
     Francisella tularensis
     Foot-and-Mouth Disease Virus
     Marburg virus
     Rinderpest virus
     Variola Major virus (Smallpox Virus)
     Yersinia pestis

    2005

     Singapore - Biological Agents and Toxins

     South Korea - Act on Prevention of Infectious Diseases

     Japan - Infectious Disease Control Laws

     Canada - CL3 CL4 facilities for Risk Group 3 & 4 are required to undergo certification

    2008

    The Danish parliament passed a law that gives the Minister of Health and Prevention the authority to
    regulate the possession, manufacture, use, storage, sale, purchase, or other transfer and disposal of
    biological agents.
    DIFFERENT ORGANIZATIONS IN THE FIELD OF BIOSAFETY

    AMERICAL BIOLOGICAL SAFETY ASSOCIATION

    It promotes biosafety as a scientific discipline and provides guidance to its members on the regulatory
    regime present in North America.

    ASIA PACIFIC BIOSAFETY ASSOCIATION

    Acts as a professional society for biosafety professionals in the Asia-Pacific region

    Active members of the International Biosafety working group are required to directly contribute to the
    development of the best biosafety practices.

    DR. CHUA TECK MEAN

    EUROPEAN BIOLOGICAL SAFETY ASSOCIATION

    Focuses on encouraging and communicating among its members information and issues on biosafety
    and biosecurity as well as emerging legislation and standards.

    BIOLOGICAL RISK ASSOCIATION PHILIPPINES

    It is a non-government and non-profit association wherein its officers and members work to serve the
    emergent concerns of biological risk management in various professional medical, agricultural,
    technological and biological sectors throughout the Philippines.

    END OF PART 1

    You might also like