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  • Patho of Invasive Duct Carcinoma

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    BESA JERIC FLORES
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    Invasive ductal carcinoma is the most common type of breast cancer. It is caused by genetic and lifestyle risk factors that increase estrogen exposure and disrupt DNA repair mechanisms in breast cells. Key risk factors include family history of breast cancer, older age, nulliparity, early menarche, late menopause, radiation exposure, obesity, smoking, and alcohol consumption.

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    PATHO OF INVASIVE DUCT CARCINOMA

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    Invasive ductal carcinoma is the most common type of breast cancer. It is caused by genetic and lifestyle risk factors that increase estrogen exposure and disrupt DNA repair mechanisms in breast cells. Key risk factors include family history of breast cancer, older age, nulliparity, early menarche, late menopause, radiation exposure, obesity, smoking, and alcohol consumption.

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    31 views3 pages

    Patho of Invasive Duct Carcinoma

    Uploaded by

    BESA JERIC FLORES
    Invasive ductal carcinoma is the most common type of breast cancer. It is caused by genetic and lifestyle risk factors that increase estrogen exposure and disrupt DNA repair mechanisms in breast cells. Key risk factors include family history of breast cancer, older age, nulliparity, early menarche, late menopause, radiation exposure, obesity, smoking, and alcohol consumption.

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    PATHOPHYSIOLOGY OF INVASIVE DUCT CARCINOMA

    RISK FACTORS

    Hereditary Advance Age ↑ Estrogen exposure  Previous breast Lifestyle


     Nulliparity, early cancer or carcinoma
    Family History Female
    menarche, late in situ (CIS)
    menopause, late 1st  Radiation Exposure
    pregnancy
    Alcohol ↑ BMI Smoking
    Mutation of ↑ proto- Family
    consumption
    tumor oncogenes history of
    suppressor (HER2 genes) breast Adipocytes Early
    genes cancer or produce initiation,
    ↑ serum estrogen longer
    other
    ↑ tissue estrogen from duration
    cancers, rare
    Can’t repair
    growth genetic
    damaged
    syndromes
    DNA or No
    BREAST
    destroy regulation
    CANCER
    affected cells

    Non-Invasive Invasive Breast


    Breast Cancer Cancer

    Ductal Carcinoma in Lobular Carcinoma in Paget Disease Invasive Ductal Invasive Lobular Medullary Inflammatory
    Situ (DCIS) Situ (LCIS) Carcinoma Carcinoma Carcinoma Breast Carcinoma

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