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DRUG STUDY

Name of the Patient: Age: 96 y/o Sex: Female Name of Student: _____________________
Civil Status: __________ Religion: Rm/Bed No. _________ Area: ______ Level/ Block: BSN IV-A
Address: Date Submitted: May 26, 2023
Date of Admission: Diagnosis: ________________________ Rating: ______________________________

MEDICATION Classification/ Action Indications Contraindications Side Effects Adverse Effects Nursing Responsibilities
Generic name: Drug Classification Skin and skin structure This drug is Confusion Seizures BEFORE:
infections contraindicated to
Piperacillin/ Therapeutic Class: Dizziness Clostridium Difficile Verify the doctor’s order
patients with:
Tazobactam associated diarrhea regarding the medication.
Anti-infectives
Hypersensitivity to Headache
Brand name: Acute Generalized
Pharmacologic Class: penicillin, beta-lactams, Observe the ten rights of
Exanthematous Pustulosis
Tazocin cephalosporins, or Insomnia medication
Extended spectrum tazobactam (cross Stephen Johnson Syndrome administration.
Usual dosage/ penicillin sensitivity may occur) Lethargy
frequency: Drug Action: Question for history of
Use Cautiously in:
Constipation allergies and full
IV (Adults): Most Piperacillin: Binds to Renal impairment medication history;
infections—3.375 g q bacterial cell wall (dosage reduction or Nausea screen for interactions.
6 hr. membrane, causing cell increased interval
death. Spectrum is recommended if CCr Vomiting Educate and verify patient
Usual route
extended compared <40 mL/min); Sodium and SO’s understanding
Intravenously with other penicillin. restriction; Critically ill about the medication.
Tazobactam: Inhibits patients (increased risk
Drug order: of renal failure; use Check the medication
beta-lactamase, an
enzyme that can alternative antibiotic, if three times.
destroy penicillin. possible)
DURING:

Observe patient for signs


Therapeutic Effect:
and symptoms of
Death of susceptible anaphylaxis (rash,
bacteria. pruritus, laryngeal edema,
wheezing). Discontinue
Absorption: the drug and notify health
Distribution: Widely care professionals
distributed. Enters CSF immediately if these
well only when occur.
meninges are inflamed.
Keep epinephrine,
Crosses the placenta
antihistamine, and
and enters breast milk
resuscitation equipment
in low concentrations.
close by in the event of
Protein binding: an anaphylactic reaction.

Metabolism and Monitor bowel function.


Elimination: Piperacillin Diarrhea, abdominal
(68%) and tazobactam cramping, fever, and
(80%) are mostly bloody stools should be
excreted unchanged by reported to health care
the kidneys. professional promptly as
a sign of Clostridium
Half-life: Adults: 0.7– difficile-associated
1.2 hr diarrhea (CDAD)
Onset: Rapid
Assess skin reactions
Peak: End of Infusion (rash, fever, edema,
mucosal erosions or
Duration: 4-6 hour ulcerations, red or
inflamed eyes). Monitor
patient with mild to
moderate rash for
progression. If rash
becomes severe or
systemic symptoms
occur, discontinue
piperacillin/tazobactam.

Evaluate renal and


hepatic function, CBC,
serum potassium, and
bleeding times prior to
and routinely during
therapy.

AFTER:

Advise patients to report


rash and signs of
superinfection (black furry
overgrowth on tongue,
vaginal itching or
discharge, loose or foul-
smelling stools) and
allergy.

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