1. Paroxetine inhibits the CYP2D6 enzyme.
2. Smoking is an inducer of the CYP1A2 enzyme which can cause oral contraceptive failure.
3. Rifampicin, fluconazole, and amphotericin B can cause oral contraceptive failure.
1. Paroxetine inhibits the CYP2D6 enzyme.
2. Smoking is an inducer of the CYP1A2 enzyme which can cause oral contraceptive failure.
3. Rifampicin, fluconazole, and amphotericin B can cause oral contraceptive failure.
1. Paroxetine inhibits the CYP2D6 enzyme.
2. Smoking is an inducer of the CYP1A2 enzyme which can cause oral contraceptive failure.
3. Rifampicin, fluconazole, and amphotericin B can cause oral contraceptive failure.
2. Smoking (Tobacco): 1A2 inducer 3. Which cause oral contraceptive failure? Fluconazole or Amphotericin B or Rifampicin or L-thyroxin 4. What does of Feso4 H2o should be given to get 100mg of elemental iron (170mg) 5. Ascorbic acid used with methenamine to acidify urine increase formaldehyde which has antibacterial activity 6. Metformin dose newly diagnosed patient --- 500mg OD 7. Codeine metabolite --- Morphine 8. Not affected in acute asthma –5HT 9. Levodopa concentration is effected with – (dopamine, carboxylase inhibitor, protein diet) 10. Saturation of substrate leads to ---- increase in reaction, decrease in reaction, reaction stop, no change 11. Labetalol is : Alpha and beta blocker. 12. Starting cone 200, tl/2 = 6 hr, Cone after 24hr? ---- 12.5hr 13. Penicillin MOA --- cell wall inhibitor 14. Hepatic blood flow 72, perfusion 90, F? 80% 15. Methyldopa – Hemolytic anemia 16. 5 a-reductase inhibitor: Finasteride 17. 0.3ml 1 X 10-4 & 2 X 10-6 moles 18. 2.66 mg KCI 3 mmole/L & 90 ml 19. Digoxin and Amiodaron interaction --- 20. What would be the better outcome in public health (early detection of disease and treatment, increase diagnosis, increase healthcare worker load) 21. Long term use of prednisone causes on face what------- Starie (Telangectiasis) 22. Drug safe in iv bolus: salbutamol 23. Epinephrine act primary on (beta 1) 24. What counseling not necessary female patient taking oral contraceptives --- 25. Thrombocytopenia means --- 26. Type I reaction is caused by: lgE 27. epoprostenol ---- It inhibits platelet activation 28. effective vasodilator. 29. Formoterol onset? 1-3 min 30. Higher in blood --- erythrocytes 31. NPH diff from glargine by: shorter duration of action 32. 30ml 1.5 ppm, 6000 L, 30% 33. Not used as antianginal agent: verapamil - perindopril (ACEI) - Metoprolol 34. Not appear in asthma ... 5HT 35. Leukocytosis: fr leukocytes 36. Cause miosis (cholinergic agonist) ------ pilocarpine 37. osmotic diuretic ... Mannitol 38. Doxorubicin > cardio toxicity 39. Least likely to cause hepatoxicity: Amoxicillin, PCM, Flucloxacillin 40. Not for tachyarrhythmia: Atropine 41. which laxative make dependance--------Biscodyl 42. Longest-acting opioid -- fentanyl patch (if not present > Methadone) 43. Traveler diarrhea which antibiotics for treatment? x-floxacin 44. Methotrexate toxicity give? Leucovorin (Ca folinate, folinic acid), ** for prevention: Folic acid 45. Selegeline -- MAO B Inhibitor 46. Penicillinase resistant AB? Oxacillin, cloxa, dicloxa, flucloxa nafcillin, Methicillin 47. Procain degradation: Hydrolysis 48. Atenolol in angina: decrease HR, decrease Oxygen demand 49. Which is not measured by immunoassay? Electrolyte 50. Diphenoxylate is given for? Acute uncomplicated diarrhea 51. Amphotericin B used for Aspergillus 52. Drug which is used both IV and topical --- (Amphotericin B, Miconazole, Fluconazole) 53. Primary organ for drug metabolism --- Liver 54. Cross placenta? lgG 55. Longest wash our period – Fluoxetine 56. Counseling for folic acid - --- folic acid up to 12 weeks 57. Least to absorb the drug (buccal cavity, stomach, intestine, ileum) not sure 58. Not the side effect to Thyroxin (heat intolerance, weight gain, fine tremor, 59. Not indicated live vaccine in (above 50 years, 1 year ago had a zoster, immunocompromised, kidney failure) 60. Not side effect of paroxetine -- 61. Tumor lysis syndrome cause (Hyperkalemia, hypernatremia, hypokalemia, hyponatremia) 62. Impact of Darpopoietin (Erythrocytes) 63. Lithium cause – Diabetes insipidus 64. HTN + Diabetes: ACE inhibitors 65. Cross sensitivity between penicillin and cephalosporin 4-10%- 2 - 3% 66. what is unusual for Ace inhibitors: -increased creatinine & hyperkalemia , decreased creatinine & hyperkalemia 67. Counseling for GTN (amber glass tight container with cotton) 68. Impulse carries away from cell body (effector, Axon, dendrites,) 69. What increase in heart failure (CKP, LDH, ) 70. Buffer used for which dosage form (IV, Suppositories, Oral disintegrate tablet) 71. Anemia in CKD (Normochromic normocytic, normochromic microcytic) 72. Pressure in more (Arteries or Veins) 73. Wrong about camphor (Eutetic, insoluble in water, soluble in ethanol) 74. Warfarin is antagonized by (St. wort, ginko biloba, grapefruit,) 75. Lanolin calculation wool fat from recall (50+6) 76. Concentration dependent antibiotic (Vancomycin, Aminoglycosides, Azithromycin, Doxycycline) 77. Ketone group (phenobarbitone) 78. Bactericidal antibiotic 79. Traveller diarrahe (Norfloxacin) 80. Cause of meningitis in 2 years 81. Attached to surface of (ribosomes) 82. MAO type A Selective – Moclobemide 83. MAO type B Selective --- Selegiline 84. Drug of choice in Pinworn – Mebendazole 85. Cardiac glycoside --- steroid nucleus 86. Benefit of moderate exercise in diabetes patient (reuptake of glucose) 87. Chondrocytes (OA) 88. Drug in pregnancy (Labetalol) 89. Drug caution in depression with hypertension (Methyldopa) 90. Drug contraindicated in acute porphyria (ketamin, propofol, phenobarbital) not sure 91. Prostaglandin --- Fatty acid 92. Vancomycin – redness, flushing 93. Causative agent for meningitis age 2-10 years Neisseria 94. Meningitidis (less than 2 -- H.lnfluenza) 95. Bradykinin- Vascular smooth muscle relaxation 96. Atenolol + Verapamil- Bradycardia “additive effect” 97. Productive cough for hypertensive patients---- Guaiphenesin 98. Protective layer on stomach-- Sucralfate 99. Miosis------ Pilocarpine 100. Side effect of aminoglycoside--------- Nephrotoxicity 101. Precursor of Histamine--- Histidine 102. Laxative dependence----- Bisacodyl 103. Verapamil and Cyclosporin interaction----- Increase Cyclosporin 104. Prevention of Asthma------------ Inhaled Corticosteroid 105. Diphenoxylate for---------- Acute uncomplicated diarrhea 106. NE to Epinephrine------ Methylation 107. Osmotic diuretic-------- Mannitol 108. Amphotericin B----- Aspergillosis 109. Time to reach steady state 12hrs 110. MOA of Corticosteroids-----Inhibits Phospholipase A2 111. Acamprostate duration-----3 months 112. Drug having ketone structure-----Prednisolone 113. Dose adjustment need after smoking-----Olanzapine 114. Bond Between Organophosphorus and Chlorine----- (don’t know the options) 115. What should be immediate action patient overdose with paracetamol with no symptoms of toxicity (NAG, Taken test, sodium bicarbonate, water) 116. Remaining calculations mmol, all new
NOTE: No question from any structure, no question from stereochemistry