Abortion
Abortion
Presented to/
Dr. Fatima Ibrahim
Definition of abortion
Is the expulsion of the fetus prior to viability, which is considered to
be 20 weeks gestation or weight of less than 500g?
Abortions are either spontaneous (occurring naturally) or induced
(occurring as a result of surgical or medical means).
Risk factors for abortion
There are several risk factors associated with a higher rate of
pregnancy loss.
Age — advancing maternal age is the most important risk factor for
spontaneous miscarriage in normal women.
Causes of abortion
The etiology of abortion of chromosomally and structurally normal
embryos/fetuses in apparently healthy women is particularly
unclear.
Chromosomal abnormalities:
classification of abortion:
Abortion
Spontaneous Induced
Septic (common)
1-threatened abortion:
Any vaginal blood loss in early pregnancy should be thought of as a
threatened miscarriage until shown otherwise.( The embryo is
usually live)
Clinical manifestaions:
-Blood loss may be scanty with low back pain or cramps like pain;
the pain may resemble dysmenorrhea or period pains.
-The cervix remains closed.
- the uterus is soft , with no tenderness when palpated
Medical management :-
- Uterine relaxants like ritodrine or isoxsuprine hydrochloride .
- Sedatives to prevent uterine contraction as phenobarbital 60
mg.
- Pethidine for pain.
- Human Chorionic Gonatrophin (HCG) injections can also be
prescribed to support the pregnancy.
Progesterone supplements are given if progesterone deficiency is
suspected to be the cause of the threatened abortion
2-Inevitable or imminent abortion
If the treatment of threatened abortion is not adequate or timely, the
abortion may become inevitable.
-is the case of pregnancy that cannot be saved, because of a good
portion of the placenta has been detached and the cervical os is
dilating
-The woman presents with bleeding, often heavy (that the mother is
in a shocked state) with clots or products of conception.
-The cervix is dilated and on examination, the membranes may
rupture products may be seen or protruding through the os
-the uterus if palpable, is smaller than expected and strong uterine
contractions may be felt abdominally.
-the accompanying backache and intermittent lower abdominal pain
are intense.
b) Complete miscarriage:
-all the products of conception are expelled.
-pain subsides and bleeding is slight and gradually diminishes.
-the cervix is found closed or reforming
-The uterus is becomes smaller in size and is firmly contracted on
examination, and an empty cavity is seen on ultrasound.
Genetic factors
Structural anomalies :
1- Uterine conditions a uterine malformation is considered to
cause about 15% of recurrent miscarriages. The most
common abnormality is a uterine septum
2- Cervical conditions :incompetent cervical os which results
in midtrimester spontaneous abortion ,usually after 16
weeks gestation or early preterm delivery
*the abortion tends to be rapid, painless and bloodless.
Infectious causes
including listeriosis, toxoplasmosis, and certain viral infections
(rubella, herpes simplex, measles, cytomegalic virus).
Thrombophilia
Endocrine causes
As hypothyroidism , Unrecognized or poorly treated diabetes -
mellitus , and polycystic ovary syndrome
Immunologic causes as systemic lupus erythematous.
Environmental causes
The lifestyle of pregnant women appears to affect the
rate of habitual abortion as smoking, alcohol, and heavy coffee
consumption can adversely affect fetal development.
Ovarian factors: as inadequate luteal phase with insufficient
secretion of progesterone.
Management:
Prophylactic therapy should be started when the woman is in
a non pregnant state through prevention of its causes.
Investigations to identify the cause :
– blood tests for hormonal levels and for infections, blood
glucose level, USG for uterine causes, HSG to identify
cervical incompetence and for uterine causes.
1-find the cause of habitual abortion and treat it appropriately
and adequately
2-Hormonal deficiencies and infections are
treated by medicines and bed rest.
3-cervical cerculage at 14 weeks, which remains in place until
38 weeks or until onset of labor when it is removed
4- Missed Abortion
In missed abortion the fetus dies but the products of
conception are retained for a prolonged period of time (2 or
more weeks).Signs and symptoms of a missed abortion include
the following:
1. Normal early pregnancy without accompanying
presumptive and probable signs of pregnancy
2 .Vaginal spotting or bleeding or lower abdominal or back
pain at the time of death of the fetus (may or may not occur)
3 .Fundal heights not only ceases to increase but after a while
the uterus becomes smaller (due to maceration of the fetus and
absorption of the amniotic fluid)
4. Regression of mammary changes of pregnancy
5. The woman often loses a few pounds in weight
6 .-the woman may report a brownish vaginal discharge .the
cervix is closed
7 .No fetal heart tones when anticipated by dates
8. If the fetus is retained beyond 6 weeks there is potential
development of disseminated intravascular coagulopathy
(DIC).
Therapeutic management:
-When a woman presents with these signs and symptoms,
an ultrasound examination is ordered for confirmation
Of fetal death.
-evacuation to avoid the potential serious complications:
*uterus is less than 12 weeks: dilation and evacuation.
5-septic abortion:
-infection superimposed on any type of abortion (especially,
missed, incomplete, and therapeutic)