Pctbiochem Agmc23

AGARTALA GOVERNMENT MEDICAL COLLEGE
Dept. of Biochemistry
Date- 01st MARCH,2023 Marks: 40 Time: 1 hour
PART COMPLETION TEST (Written)

1. Enumerate the role of Vitamin D on Calcium homeostasis.
2. Explain why: 2x3-6

a) Peripheral neuropathy is commonly seen with anti-tuberculosis drugs.
b) Bleeding of gums is seen in Vitamin C deficiency.
c) Haemoglobin is an allosteric protein.
3. What is 'salting in' and 'salting out'? Define Tertiary structure of protein with
example. 2+3=5
4. Write short notes on: 3x3=9

a) Beta pleated sheets
b) Zwitterions
c) Oxygen dissociation curve
5. Define enzyme specificity. Classify and give suitable exanples. 1+3-4
6. Why enzymes are used as markers for disease 3
7. Write the properties of allosteric enzymes. 3
8. Write a note on slructure and types of haemoglobin.

Date- 03rd May, 2023 Marks: 40 Time: 1 hour
PART COMPLETION TEST Written)

Attempt all the questions with diagrammatic representation wherever necessary
1. Write in brief about the hormonal regulation of glycogenolysis. 5
2. How fatty acids are transported inside mitochondrial membrane for metabolism with
special focusing on long chain faty acid. 4
3. Enumerate the causes leading to Fatty liver. 3
a. Importance of formation of Lactate in anaerobic glycolysis.

b. TCA cycle as amphibolic pathway
c. Lipotropic factors and their mechanism of action
5. What are the components of FAS Complex? Enumerate its metabolic advantages. 4
6. Explain why: 3*$=|5
a. High fructose consumption is related to Atherosclerosis

b. Hyperuricemia is seen in Von Gierke's Disease
c. Patients with G6PD deficiency are resistant to malaria
d. Chronic alcohol consumption induces fatty liver.
e. Overproduction of ketone bodies takes place in uncontrolled Diabetes Mellitus and
prolonged starvation.
Date- 14th June, 2023 Marks: 40 Time: 1 hour
PART COMPLETION TEST(Written)

Attempt all the questions with diagrammatic representation wherever necessary

a) Biochemical function of Zinc and its deficiency diseases.
b) Iron absorption in mucosal cells of GIT.
c) Biochemical basis of Menke's Disease & Wilson's Disease.
d) Phenylketonuria.
3x6=18
2. Explain why:
a) Cytochrome P450 is having Monooxygenase function.
b) Selenium and Vitamin E are having synergistic action.
c) Ammonia is toxic to the body.
d) Phenylalanine and Tyrosine are both glucogenic and ketogenic amino acids.
e) Allopurinol is used in the treatment of Gout.
f) Methotrexate is used as an anti-cancer drug.
6
3. Write on synthesis of Catecholamines.
AGARTALAGOVERNMENT MEDICAL COLLEGE
Date- 4th Jan, 2023 Marks: 40 Time: 1hour
PART COMPLETION TEST (Written)
1. Mention the sources of Omega -3-fatty acids and it's clinical importance. 4
2 What is cell compartmentalization? Why it is important in Eukaryotes?
Detine markers enzymes. Mention the markers enzymes focusing tò reilt'ar

rganelle.
+ Write a note on composition and importance of glycolipid. what is L:S ratio? 5
3. Enurnerate the properties of phospholipid. 3
6. Write short note on the following. ix3=9

an Mutarotation of monosaccharide.
b) Hvaluronic acid and its clinical inportance
) Cytoplas1m and cytoskeleton.
Iarlain why.
Plysician advice to apalient witli consti;pation to consume cellu!os.
b) Old people do not like to drink cow's milk.
c) Lysosome is known as suicidal bag.
TNEDI
DEPRTIMENT OF BIOCHEMISTRY
AGMC & GBP HOSPITAL
PART COMPLETION TEST 5
DATE 23/o8/2023 TIME:9.00 AM -10.00 AM MARKS= 40
ATTEMPT ALL THE QUESTIONS WITH SCHEMATIC DIAGRAMS

WHEREVER NECESSARY
1. Enumerate the causes of DNA damage. Write the name of repair

mechanism involved in DNA damage. 3+2=5
2. Write short notes on: 4x3= 12
a. Okazaki fragnents
b. Post transcriptional modifications
c. Chaperones & its biological importance
d. Wobble hypothesis & its importance
3. What do you mean by 'Genetic code'? Mention its different
characteristics. 2+4-6
4. Write in brief about the requirements for protein biosynthesis. 4
5. What is 'Lac operon'?Highlight on 'Lac operonModel'. 2+5-7
6. Write a note on Bacteriophage. 3
Ix3=3
7. Explain why:
i) Chloramphenicol is used for the treatment of Enteric fever.

Pctbiochem Agmc23

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AGARTALA GOVERNMENT MEDICAL COLLEGE

PART COMPLETION TEST (Written)

2. Explain why: 2x3-6

4. Write short notes on: 3x3=9

5. Define enzyme specificity. Classify and give suitable exanples. 1+3-4

6. Why enzymes are used as markers for disease 3

7. Write the properties of allosteric enzymes. 3

8. Write a note on slructure and types of haemoglobin.

PART COMPLETION TEST Written)

1. Write in brief about the hormonal regulation of glycogenolysis. 5

3. Enumerate the causes leading to Fatty liver. 3

4. Write short notes on: 3x3=9

a. Importance of formation of Lactate in anaerobic glycolysis.

6. Explain why: 3*$=|5

a. High fructose consumption is related to Atherosclerosis

PART COMPLETION TEST(Written)

1. Write short notes on: 4x4=16

PART COMPLETION TEST (Written)

Detine markers enzymes. Mention the markers enzymes focusing tò reilt'ar

+ Write a note on composition and importance of glycolipid. what is L:S ratio? 5

3. Enurnerate the properties of phospholipid. 3

6. Write short note on the following. ix3=9

ATTEMPT ALL THE QUESTIONS WITH SCHEMATIC DIAGRAMS

1. Enumerate the causes of DNA damage. Write the name of repair

2. Write short notes on: 4x3= 12

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