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IOM Question Collection
IOM Question Collection
CONTRIBUTERS:
- AMISH CHAUDHARY [ IOM, 20TH BATCH]
B.Pharmacy Question Paper Collection,IOM
For First Year
[Anatomy: 2077]
1. Differentiate between a skeletal muscle and smooth muscle. Draw a neat labeled diagram of each of
them. 2+1.5+1.5=5
2. List the organ of urinary system. Draw a well labeled diagram of nephron. Mention the function of
kidney. 1+2+2=5
3. Describe the gross structure of thyroid gland with applied aspects. 4+1=5
2. Mention the name of primary and secondary lymphoid organs. Describe the gross structure of lungs.
(1+3)
3. Describe the structure of Human Heart with well labeled diagram. Define pericardium and
mediastinum. (3+1)
4. Describe the structure of spinal cord. Classify neuron on the basis of polarity (2+2)
5. Describe the structure of liver with well labeled diagram. Define ductus venosus and liagmentum
teres hepatis. (3+1)
[Physiology: 2077]
1. Define blood. What is the composition of blood? List the functions of blood. 1+2+3=6
2. List the layers of respiratory membrane. Explain the mechanism and factors affecting diffusion of
gases across the respiratory membrane. 1+5=6
3. List the composition and function of pancreatic juice. What is steatorrhoea? 2+3+1=6
4. Explain the effects of growth hormone on different organ system of the body. Mention the feactures
of hypo and hyper secretion of growth hormone. 4+2=6
a. Functions of kidneys
b. Ovarian cycle
c. Cardiac output
B.Pharmacy Question Paper Collection,IOM
For First Year
d. Pathophysiology of Mysthenia Gravis
3. Explain the excitation contraction coupling in a skeletal muscle. What is isotonic contraction and
isometric contraction? (3+1+1)
4. Explain the different methods of oxygen transport in blood? List the different types of Hypoxia. (3+2)
6. Write the differences between upper motor neuron paralysis and lower motor neuron paralysis. (5)
[Pathology: 2077]
1. Describe the signs and symptoms of viral hepatits. Give its laboratory diagnosis. 2+2=4
2. List the factors causing inflammation. Describe the vascular event in acute inflammation. 2+2=4
2. Features of hypothyroidism.
a. Hybridoma technology
c. Transgenic animal
[Biochemistry: 2077]
1. a. Explain different types of enzyme inhibition. What is the role of Michaelis Menten on this. [6]
2. a. Explain with flow chart why anerobic glycolysis gives 2 ATP only?
3. Explain the process of fatty acids oxidation to liberate energy. List the factors that favor ketogenesis.
[6+2=8]
a. ammonia
b. bilirubin
5. Describe the process of DNA extraction froma given buccal swab sample. Outline the components of a
polymerase chain reaction. [5+5=8]
a. prostaglandins
B.Pharmacy Question Paper Collection,IOM
For First Year
b. amino acids
c. complex lipids
d. heteropolysachharides
7. Classify fat soluble vitamins. Describe the RDA, sources, biological functions and deficiency
manifestation of fat soluble vitamins. [1+7=8]
8. Define and classify tumor markers. Write a short note on their clinical significance with example.
[6+2=8]
a. Propranolol [5]
3. Classify non-steroidal anti-inflammatory agents giving example from each class. Write the structure,
mechanism of action, uses and adverse effects of Paracetamol. [3+7=10]
5. Explain SAR of sympathomimetic agents with suitable examples. Show MOA of irreversible
cholinesterase inhibitors and cholinesterase reactivators. [5+5=10]
6. Explain SAR of benzodiazepines with suitable examples. Show MOA and synthetic scheme of
Phenobarbitone. [4+3+3=10]
B.Pharmacy Question Paper Collection,IOM
For First Year
7. Describe stereochemistry and metabolism of steroids. Discuss MOA of Sildenafil Citrate.
[4+3+3=10]
[Pharmacology I: 2077]
1. Classify antihypertensive drugs with example. Write down pharmacological actions, therapeutic uses
and side effects of Amlodipine. 4+2+2+2=10
3. Define and classify sedative and hypnotics with examples. Discuss the MOA and uses of
Benzodiazepines. 4+3+3=10
i. Risperidone
ii. Digoxin
5. Classify adrenergic drugs with examples. Write the pharmacological effects, therapeutic uses and side
effects of Salbutamol. 4+2+2+2=10
6. What is epilepsy? Discuss the types of epilepsy. Classify antiepileptic agents with examples from each
class. Write the pharmacokinetics, uses, MOA, and side effects of Phenytoin. 2+4+2+2=10
7. Define adverse drug reactions. Describe in detail the different types of ADR with suitable examples.
2+8=10
8. Define haemostasis. Describe in detail the mechanism of action, ADR, monitoring parameters and
uses of oral anticoagulants. 2+3+2+3=10
B.Pharmacy Question Paper Collection,IOM
For First Year
b. How many grams of FeSO4.7H2O should be weighed to prepare 250 ml of 20ppm solution of
sodium fluoride? 5
3. Define dentifrices? Classify the dental products and explain the functions of dental products. Explain
test for purity, assay and medical uses of sodium fluoride. 2+4+4=10
4. explain the test for purity, properties, assay and medical uses of:
a. Hydrogen peroxide 5
5. Explain the stereochemistry and mechanism of SN1 and SN2 reactions. What happens when 2,2
dimethyl-1,3-bromo butane undergoes reaction through SN1 and SN2 paths? 7+3=10
b. How electrophilic addition reaction does differ from free radical addition reaction? Explain the
mechanism. 6
3. What are the sources of impurities in pharmaceutical substances? Explain the limit test for sulphate
or lead. (10)
4. What are topical gastro intestinal agents? Explain preparation, Test for purity, Assay and Medicinal
uses of ammonium chloride. (10)
Or
5. What are topical agents? Explain preparation, Test for purity, Assay and Medicinal uses of Zinc
sulphate.
6. calculate the weight of heptahydrated ferrous sulphate required to prepare 100ml, 20 ppm sulphate
solution. (5)