ANTENOR ORREGO PRIVATE UNIVERSITY

SYLLAB
ACADEMIC SEMESTER 202310

I GENERAL INFORMATION

1 FACULTY(S) :HUMAN MEDICINE

2 PROGRAM(S) OF STUDIES :HUMAN MEDICINE
3 SUBJECT :MICROBIOLOGY
4 MODALITY :PRESENTIAL
5 CODE :MEHU-509
6 STUDY CYCLE :05
7 CREDITS
:3
8 LEVEL
:UNDERGRADUATE
9 TOTAL SEMESTER HOURS
:85
10 TOTAL WEEKLY HOURS
:5
11 START DATE
12 DUE DATE :03/04/2023
13 DURATION WEEKS :27/07/2023
14 PREREQUISITES :17
:MEHU-137 OR MEHU-610
: ARAUJO JIMENEZ, ARMANDO; ASMAT MARRUFO,
PERCY ESTEBAN; AVILA VEREAU, ELIO FERNANDO;
15 TEACHER(S) GONZALEZ CABEZA, JOSE GUILLERMO; MANAY
BARRERA, JULIO AMERICO; REYNA LOPEZ, LENNIS
ANTONIO; SILUPU GARCIA, CARMEN ROSA; TORRES
CHICLAYO, KEYLA MIRELY;
: [email protected] , [email protected] ,
16 INSTITUTIONAL EMAIL [email protected] , [email protected] ,
[email protected] , [email protected] , lreynal
@upao.edu.pe , [email protected]
II SUMILLA

The Microbiology Subject corresponds to the basic area in the training of the Medical Professional, having both a theoretical and practical component. The

objective pursued is to provide the student with the formation of general and specific concepts in morphology, physiology and genetics of bacteria, viruses

and fungi; with the consequent study of its ecology and implications of microorganisms in human pathologies; Likewise, as a result of the practical

sessions, the development of certain abilities or skills in microbiological procedures is intended. The subject is divided into four academic units:

I Unit: Microorganisms and Principles of Bacteriology.

II Unit: Antimicrobials and Special Bacteriology

III Unit: Special Bacteriology and Mycology

IV Unit: Virology.

III CONTRIBUTION OF THE SUBJECT TO THE GRADUATE PROFILE

 The achievement of the planned learning in this subject contributes to the achievement of the following generic competencies, specific competencies and
subcompetences:
Generic skills:

CG3.- Searches, processes and uses information from various sources, with the support of information and communication technologies.

CG4.- Demonstrates social responsibility for sustainable development and citizen commitment at a local and global level.

CG6.- Demonstrates ability for interdisciplinary learning and research.

CG7.- Learns autonomously and adapts to changes.

CG8.- Demonstrates critical, reflective, creative and innovative thinking, leadership and the ability to work as a team, to
empre
C n O d M er P p E ro T y E e N c C to I s A . SPECIFIC TO THE SUB-COMPETENCIES
EXHAUST PROFILE 01:
Specific competence Identifies and integrates the conceptual links between basic sciences with
Understands and describes the structure and function of the human social sciences and population health, understanding the role of the doctor in
body, at the molecular and genetic, cellular, tissue, organic and the health professions and in the lives of their patients.
systems levels, and the host defense mechanisms at different stages It explains the causative agents and risk factors that determine the
of life; in health and illness situations and how it relates to the real development of the disease, and identifies the altered human behavior itself.
practice of medicine.
Specific competence 02:
Provides health care to the patient based on a diagnosis and Prepares a complete clinical history with relevant information based on
treatment with an evidence-based medicine approach for recovery communication and a thorough clinical examination with the patient, and
and rehabilitation within health systems, respecting their cultural interprets relevant laboratory , imaging and endoscopic studies.
characteristics.

IV PROGRAMMING BY LEARNING UNITS

UNIT 01 MICROBIOLOGY - GENERALITIES

1. It identifies and analyzes fundamental ideas about the objectives of microbiology in medicine, addresses aspects of cosmic and biological evolution

associated with the historical aspects of this science, the impact it has had on humanity and on the development of other sciences.

2. Identify and explain the differential characteristics of the main microbial groups, the object of study in microbiology.

3. Identify and explain the principles of bacteriology, likewise, identify the main bacterial morphologies; as well as its dyeing and cultivation

characteristics.

4. Describes microbial metabolism in energetic terms, establishing differences between aerobic respiration, anaerobic respiration, strict anaerobe,

facultative anaerobe and fermentation.

No. Weeks Thematic Contents Learning activities

 IN-PERSON ACTIVITIES THEORY 1:
Microbiology.
PRACTICE 1:
INAUGURAL CLASS: INTRODUCTION Practice 1. Biosafety in the
TO MICROBIOLOGY. Microbiology Laboratory.
Origin and Evolution of the Universe. Previous distribution of students into
Origin of life. Historical-Evolutionary tables and work groups.
Progress. Teacher's Dissertation at the Practice
MICROBIOLOGY: Table: Biosafety. Concept. Biosafety
Cosmic Evolution-Biological Evolution. standards in microbiology laboratories and
Main evolutionary historical milestones. medical centers. Biosecurity Levels.
Week 1 Microorganisms as cells. Application activities:
History of Microbiology: Historical Application of GLPs (good laboratory
periods (Koch's Postulates, Pasteur's practices), correct use of PPE or PPE and
Contributions). correct hand washing.
Linking microbiology with other sciences. Handling of microbiological material –
Classification of microorganisms: Glassware, instrumentation.
Domain: Eubacteria, Domain: Archaea, The students share their products with the
Domain: Eukarya. Characteristics: table teacher in the next class.
Similarities / Differences. Clinical case: Biosafety.
Complementary activities:
Observation and evaluation in the video
forum: (1) Pasteur and Koch, medicine
and revolution.
Reading: “History of microbiology”
IN-PERSON ACTIVITIES THEORY 2:
Conducting a conference: Principles of
Bacteriology.
IN-PERSON ACTIVITIES PRACTICE 2:
Practice 1: Microscopy and Stains.
Teacher's Dissertation at the Practice
Table: Fundamentals of Optics and
Microscopy. Handling and care of the
compound microscope.
Prepared fresh and dry.
PRINCIPLES OF BACTERIOLOGY. Dyes and colorations. Staining
Nomenclature / Classification Criteria / Techniques: Single and Double Staining
Taxes. (Gram Staining, Ziehl-Neelsen Staining).
Characteristics of Bacteria: Groupings / Importance.
Bacterial Morphology. Intracytoplasmic Application activities:
Structures: Nucleus (nucleoid) and Execution of various coloring techniques.
Bacterial Chromosome. Microscopic Observations: Bacterial
Week 2
Surface Structures: Cytoplasmic Morphology. Main Bacterial Structures:
Membrane / Cytoplasmic Structures / Cell Wall / Capsule / Spores / Cytoplasmic
Wall / Protoplasts / Spheroplasts / inclusions. Establishment of personal
Capsule / Glycocalyx / Flagella / Cilia. scientific research work topic
Differentiation Structures: Formation of (Monograph).
spores (Endospores): Sporulation and Complementary activities:
Germination. Reading: Microbial theory of disease
(Search for information about it).
Video observation: (2) "A world without
microbes", Keyzem Bioneuroemoción,
Science & view tv, May 2017.
 IN-PERSON ACTIVITIES THEORY 3:
Holding a conference: Metabolism and
Microbial Growth. IN-PERSON
ACTIVITIES PRACTICE 3:
Practice 1: Preparation of Culture
Media and Sowing Methods.
Teacher's Dissertation at the Practice
METABOLISM AND MICROBIAL
Table: Handling and correct use of
GROWTH:
material, equipment and reagents for the
Microbial Metabolism: Bacterial nutrition
preparation of culture media.
and metabolism.
Recognition of bacterial forms and their
Microbial Growth: Cell Division in
groupings.
Populations.
Practice 2: Microbial Count Methods I.
Bacterial Culture: Nutritional
Teacher's Dissertation on Practice Table:
Requirements / Chemical-Physical
Microbial Count Methods: Met. Most
Requirements.
common Direct and Indirect. Plate Count
Week 3 Growth curves. Main estimates.
Method. Mc Farland Nephelometric
Calculations: Growth Yield / Growth
Method. Estimates.
Speed / Growth Control.
Application Activities: General
Environmental factors that affect bacterial
Dissertation by the Table 1 Teacher (90
growth: Nutrients / pH / temperature /
min.): Growth curves. Main estimates.
oxygen tension / water and others.
Calculations: Growth Yield / Growth Speed
Bacteriological culture media. Action of
/ Growth Control. Absolution of
Physical - Chemical agents on bacteria:
Questionnaire and/or Clinical cases or
Radiations / temperature / acids / bases /
problems in the forum. Textbook
heavy metals / alcohols / phenols.
Readings.

UNIT 02 SPECIAL BACTERIOLOGY

Capacities to be developed in the Learning Unit:

1. Identify and explain the principles of bacteriology, likewise, identify the main bacterial morphologies; as well as its dyeing and

cultivation characteristics.

2. Identifies the groups of drugs used in the control of infectious diseases; relates them to their mechanisms of action; It also

identifies the resistance mechanisms of microorganisms to these drugs.

3. Identifies and describes the main genera and species of Gram-positive and Gram-negative bacteria of interest in human

infectious pathology; It also understands and explains the taxonomy, pathogenesis, laboratory diagnosis, infection control,

epidemiology and prophylaxis against these germs and the diseases they cause.

No. Weeks Thematic Contents Learning activities

 IN-PERSON ACTIVITIES THEORY 4:
Online evaluation of prior knowledge.
Conference: Antimicrobials, Mechanisms
of action. Main Groups of Antimicrobials.
Endurance. Review of learning results and
feedback on developed content.
IN-PERSON ACTIVITIES PRACTICE 4:
Practice 1: Microbial Count Methods 2.
Teacher's Dissertation on Practice Table:
Microbial Count Methods; Met. Counting in
Neubaur Chamber. NMP. Other methods.
Estimates.
Practice 2: Susceptibility testing to
antibacterial antibiotics.
Teacher's Dissertation on Practice Table:
CMI, CMB, Main susceptibility tests.
Application activities:
Description, conceptualization and
performance of antibacterial susceptibility
ANTIMICROBIALS tests. Met. From Kirby-Bauer.
Definitions. Antimicrobials and resistance: Absolution of Questionnaire and/or Clinical
mechanism of action; main mechanisms of cases or problems in the forum.
antibiotic resistance. Seminar : Antimicrobial Resistance
Cleaning, disinfection, asepsis and Mechanisms.
sterilization. Complementary activities:
Week 4 Video observation: (3) "Bacterial
Preparation of culture media.
Antibacterial antibiotic susceptibility testing resistance. Will common infection become
methods Identification of students with deadly?" - Parque Explora (Science by
remedial needs in the advancement of the bicycle) Colombia – Gustavo Roncancio
subject. Activities or actions for feedback Internist specialist in infectious diseases
and leveling in the progress of the subject. GRUPO MICROBA School of Microbiology
University of Antioquia – M. Sc. and Ph.D.
in basic biomedical sciences Natalia
Jiménez Quiceno MICROBA GROUP
School of Microbiology
Video observation: (4) “CURRENT
SITUATION OF ANTIMICROBIAL
RESISTANCE: CHALLENGES AND
OPPORTUNITIES" - Telehealth MINSA,
Conference of MD, Martín Yagui Moscoso.
 THEORY 5:
Online evaluation of prior knowledge and
about video.
Development of a videoconference
explaining gram-positive cocci of
biomedical importance (thematic content);
and on gram-positive bacilli.
IN-PERSON ACTIVITIES PRACTICE 5:
Practice 1: Study of Staphylococcus
aureus , Staphylococcus epidermidis ;
Alpha, beta and gamma hemolytic
Streptococcus and Enterococcus .
Cryopreservation.
Teacher's Dissertation at the Practice
Coconuts. Staphylococcus , Table: Methods for isolation and
Streptococcus and Enterococcus , main identification of Gram-positive bacteria
species of medical interest. under study.
Sporulated Bacilli: Application activities:
Bacillus, B. anthracis and anthracis. General Dissertation by the Teacher of
Clostridium, C. tetani and tetanus; c. Table 1 (90 min.): Corynebacterium
Week 5 diphtheriae and diphtheria. Listeria , main
difficile
Non-sporulated bacilli: Corynebacterium, species of medical interest. Lactobacillus
Corynebacterium diphtheriae and and Bifidobacterium Clinical case and/or
diphtheria. forum. Sample collection (pharyngeal and
Listeria , main species of medical interest. nasal secretion) and culture on blood agar,
Lactobacillus and Bifidobacterium . salt mannitol agar and Thioglycollate
medium; and those of bacterial
cryopreservation techniques.
Complementary activities:
Readings: (a) Non-sporulated bacilli:
Corynebacterium diphtheriae and
diphtheria. (b) Listeria , main species of
medical interest. (c) Lactobacillus and
Bifidoba cterium. (d) Interpreted reading of
the antibiogram of Gram-positive cocci.
(Textbooks and scientific articles).
 IN-PERSON ACTIVITIES
THEORY 6:
Online evaluation of prior knowledge
Conference: Mycobacteria, the Mtb
complex and tuberculosis.
IN-PERSON ACTIVITIES PRACTICE 6:
MYCOBACTERIA:
Practice 1: Bacteriological diagnosis of
General characteristics. Species of
Mycobacterium tuberculosis :
medical importance: Mycobacterium
Baciloscopy and Culture .
tuberculosis Complex ( Mtb Complex), M.
Teacher's Dissertation at Practice Table:
leprosy . Nontuberculous mycobacteria
Performing smear microscopy, Ziehl
(NTM).
Week 6 Neelsen staining technique, AFB
Pulmonary and extra-pulmonary
investigation and reporting of results,
tuberculosis (TB): characteristics,
preparation of traditional culture media for
pathogenesis, epidemiology, MDR-TB and
M. tuberculosis : Medio Ogawa and/or
XDR-TB, treatment.
Lowenstein Jensen (LJ). Likewise, a brief
Bacteriological and other diagnostic
mention and description of the current
techniques for Mtb .
techniques used in the diagnosis of Mtb is
made.
Application activities:
Clinical case, forum.
Complementary activities:
Readings: (a) M. leprae and leprosy. (b)
Rapid and other tests for the diagnosis of
Mtb .
IN-PERSON ACTIVITIES THEORY 7:
Online evaluation of prior knowledge.
Conference: where the recovery of
previous knowledge about the bacterial
species under study will be carried out; as
well as the explanation of their
microbiological characteristics and
virulence factors.
Review of learning results and feedback
GRAM NEGATIVE BACTERIA:
on developed content.
Treponema / Leptospira / Neisseria /
IN-PERSON ACTIVITIES PRACTICE 7:
Gardnerella.
Practice 1: Non-treponemal tests: RPR
Spirochetes, species of medical interest:
and VDRL. Diagnosis of gonorrhea.
Treponema pallidum; and syphilis.
Teacher's Dissertation at the Practice
Leptospira and leptospirosis.
Table: Conducting and interpreting non-
Cocci, species of medical interest:
treponemal tests: RPR and VDRL;
Week 7 Neisseria gonohorreae "gonococcus" and
performing cultures to detect pathogenic
gonorrhea; N. meningitidis
Neisseria species.
"meningococcus" and meningitis.
Application activities:
Gardnerella .
General Dissertation by the Teacher of
Diagnostic tests for the species under
Table 1 (90 min.): Neisseria gonohorreae
study.
"gonococcus" and gonorrhea; N.
Activities or actions for feedback and
meningitidis "meningococcus" and
leveling in the progress of the subject.
meningitis. Gardnerella.
Discussion and evaluation in workshops
on syphilis and gonorrhea. Practical test.
Textbook Readings.

Read, analyze and answer the partial

Week 8 PARTIAL EVALUATION
evaluation questions.
UNIT 03 BACTERIOLOGY AND MYCOLOGY I

2. Explains the distinctive characteristics of fungi, as well as defining the term mycosis and the different types of these.

3. Identifies and explains the main genera and species of fungi in human infectious pathology, and understanding of their taxonomic

situation, pathogenesis, diagnosis and control of infection, referring, the latter, to the treatment, epidemiology and prophylaxis of

infectious diseases.

4. Morphologically identifies the main pathogenic fungi and the mycoses they produce in humans.

No. Weeks Thematic Contents Learning activities

IN-PERSON ACTIVITIES
THEORY 9:
Online evaluation of prior knowledge.
Conference development where the
explanation and exchange of ideas about
the Enterobacteriaceae family and the
genera of medical importance will be held,
also an explanation about Yersinia pestis .
IN-PERSON ACTIVITIES PRACTICE 9:
Practice 1: Isolation and identification
of Enterobacteriaceae . Widal reaction.
Teacher's Dissertation at the Practice
Table: Identification schemes for
Enterobacteriaceae . As well as, the
FAMILY Enterobacteriaceae recognition, isolation and identification of
General and culture characteristics, Enterobacteriaceae , in selective and
antigens, virulence factors and differential culture media from clinical
pathogenesis. samples and the differentiation by
Enterobacteriaceae of medical interest: presumptive biochemistry of E. coli,
pathogenic Escherichia coli, Shigella, Shigella, Salmonella, Klebsiella, Proteus,
Salmonella, Klebsiella. Enterobacter among others.
Week 9 Yersinia pestis and plague. Practice 2: Isolation and identification
Microbiological and serological diagnosis. of Enterobacteriaceae. Widal reaction.
Widal test. Teacher's Dissertation at the Practice
of members of the Enterobacteriaceae Table: Carrying out the Widal Test.
family. Performing blood culture and its
Blood culture, urine culture and stool importance in microbiological diagnosis.
culture. Application activities:
Human microbiota; intestinal microbiota. General Dissertation by the Table 1
Teacher (90 min.): Enterobacteriaceae of
medical interest: pathogenic Escherichia
coli , Shigella, Salmonella, Klebsiella.
Yersinia pestis and plague.
Clinical case and/or forum.
Complementary activities:
Textbook Readings.
 IN-PERSON ACTIVITIES THEORY 10:
Online evaluation of prior knowledge.
Development of a conference where the
explanation of the bacterial species under
study will be made. IN-PERSON
ACTIVITIES PRACTICE 10:
Practice 1: Isolation and identification
of Vibrio cholerae , Pseudomonas
Vibrionaceae FAMILY : aeruginosa, Campylobacter jejuni and
Bacteria of medical interest, Vibrio Helicobacter pylori .
cholerae and cholera. Teacher's Dissertation at the Practice
Other Gram Negative bacilli: Table: Isolation schemes and identification
Pseudomonas, P. aeruginosa of the germs under study; as well as the
Campylobacter, C. jejuni Helicobacter, H. observation of images of cultures of
Week 10 pylori. Pseudomonas aeruginosa and Vibrio
Coccobacilli: cholerae .
Bordetella pertrusis and whooping cough Application activities:
Bartonella baciliformis and Carrión's General Dissertation by the Table 1
disease Teacher (90 min.): Other Gram Negative
Rickettsia prowazeki and exanthematous bacilli: Campylobacter, C. Jejuni, H.
typhus. pylori.Coccobacilli: Bordetella pertrusis
and whooping cough, Bartonella
baciliformis and Carrión's disease,
Rickettsia prowazeki and exanthematous
typhus.
Textbook Readings.

IN-PERSON ACTIVITIES THEORY 11:

Conference: Mycosis: M. Superficial, M.
Cutaneous, and M. Subcutaneous.
IN-PERSON ACTIVITIES PRACTICE 11:
MYCOLOGY: General Characteristics. Practice 1: Direct Examination and
Superficial mycoses: Malassezia genus . Culture of Dermatophytes.
Cutaneous mycoses: dermatophytes, Diagnosis of opportunistic fungi.
genera Epidermophyton, Microsporum General Dissertation by the Teacher of
and Trichophyton Table 1 (90 min.): Cutaneous mycoses:
Subcutaneous mycoses: Dermatophytes, genera Epidermophyton,
genus Sporothrix . Microsporum and Trichophyton
Identification of students with leveling Teacher's Dissertation at the Practice
Week 11
needs in the advancement of the subject. Table: Sampling in Mycology, the
Activities or feedback actions in the recognition of fungal structures in a clinical
progress of the subject. sample and in cultures; Likewise, isolation
Direct examination and culture of clinical schemes for dermatophytes and
samples from patients with superficial and opportunistic fungi.
cutaneous mycoses. Application activities:
Direct examination and culture of the fungi Clinical case, forum.
under study Textbook Readings.

UNIT 04 MYCOLOGY II AND VIROLOGY

Capacities to be developed in the Learning Unit:

1. Explains the distinctive characteristics of fungi, as well as defining the term mycosis and the different types of these.

2. Identifies and explains the main genera and species of fungi in human infectious pathology, and
3. understanding of its taxonomic situation, pathogenesis, diagnosis and control of infection, the latter referring to the treatment,
epidemiology and prophylaxis of infectious diseases.
4. Morphologically identifies the main pathogenic fungi and the mycoses they produce in humans.

No. Weeks Thematic Contents Learning activities

IN-PERSON ACTIVITIES THEORY 12:
Conference: Systemic Mycoses. IN-
PERSON ACTIVITIES PRACTICE 12:
Practice 1:
Teacher's Dissertation at the Practice
Table: Macroscopic and microscopic
Systemic mycoses: genera Histoplasma,
recognition of the fungi studied.
Blastomyces, Coccidioides and
Application activities: General
Week 12 Paracoccidiodes .
Dissertation by the Table 1 Teacher (90
Opportunistic mycoses: Candida,
min.): Opportunistic mycoses: Candida,
Cryptococcus, Aspergillus genera .
Cryptococcus, Aspergillus genera.
Clinical case, forum.
Textbook Readings.

IN-PERSON ACTIVITIES THEORY:

Online evaluation of prior knowledge.
Conference: Virology. General
characteristics, Origin, Classification.
Cytopathic effects.
Explanation about the Herpesviridae
VIROLOGY: Characteristics and family.
properties. Origin. Classification. Stages of IN-PERSON ACTIVITIES PRACTICE 13:
its replication. Viral Genetics. Viral Practice 1: DNA extraction .
pathogenesis. Virulence factors. Entry and Teacher's Dissertation at the Practice
dissemination of the virus in the host, Table: Viral diagnosis methods. In
transmission. addition, the methodology for extracting
Week 13 Bacteriophages. nucleic acids in microbial samples will be
Herpesviridae Family : explained.
Herpes Simplex Virus 1 and 2. Application activities:
Varicella zoster virus Cytomegalovirus. General Dissertation by the Teacher of
Epstein Barr virus. Table 1 (90 min.): Herpesviridae Family:
Viral diagnosis methods. Herpes Simplex Virus 1 and 2. Varicella
Extraction of DNA. zoster virus. Cytomegalovirus. Epstein
Barr virus. General Seminar: Viral
diagnosis methods.
Clinical case or forum.
 IN-PERSON ACTIVITIES THEORY 14:
III unit online evaluation.
Development of a videoconference where
the recovery of previous knowledge and
RESPIRATORY VIRUSES:
explanation of the microbes under study
Orthomyxoviridae : influenza virus.
will be carried out.
Coronaviridae .
IN-PERSON ACTIVITIES PRACTICE 14:
Enterovirus:
Practice 1: Diagnosis of Hepatitis B
Picornaviridae : genus Enterovirus :
Teacher's Dissertation at the Practice
poliovirus.
Table: Serological tests to detect HBsAg.
Week 14 Viral hepatitis: HAV, HBV, HCV, etc.
Application activities:
Retrovirus:
General Dissertation by the Teacher of
Oncovirinae : HTLV
Table 1 (90 min.): Retrovirus:
Lentivirinae: HIV-AIDS.
Oncovirinae : HTLV, Lentivirinae: HIV-
DNA viruses oncogenes:
AIDS. Discussion evaluated in working
Papillomaviridae : HPV.
tables on the SARS-CoV-2 pandemic that
Viral diagnosis methods.
produces COVID-19.
Complementary activities: Watching
videos (7): “The flu and the immune
system” , (8): To define SARS-CoV-2
(COVID-19) Reading: (a) The poliovirus.
(b) HTLV. (c) Papillomaviridae : HPV. (d)
Molecular methods in virological
diagnosis: PCR
IN-PERSON ACTIVITIES THEORY 15:
Online evaluation of prior knowledge.
Conference: Exanthematous Viruses:
IN-PERSON ACTIVITIES PRACTICE 15
Practice 1: Immunochromatography.
Teacher's Dissertation at the Practice
Table: Conducting and rationale for
Immunochromatography tests. Also, the
EXANTEMATIC VIRUSES: explanation of PCR and its best-known
Paramyxoviridae , genus Morbillivirus : formats.
measles virus; and genus Rubivirus : Application activities:
rubella virus. General Dissertation by the Teacher of
Rabies virus, and arboviruses: Table 1 (90 min.): Rabies virus, and
Week 15
Rhabdoviridae , genus Lyssavirus : rabies arbovirus: Rhabdoviridae , genus
virus Lyssavirus : rabies virus. Arbovirus :
Arbovirus : Flaviviridae , genus Flavivirus : Flaviviridae , genus Flavivirus : yellow
yellow fever and dengue viruses. Zika, fever and dengue viruses. Zika,
Chikungunya. Chikungunya.
Clinical case and/or forum.
Practical test.
Complementary activities:
Video observation (9): “Zika: history of
an epidemic” | DW Documentary,
Textbook Readings

Read the exam carefully and proceed to

Week 16 FINAL EXAM
answer the evaluation,
Answer appropriately to each question
Week 17 Substitute exam
asked.
V METHODOLOGICAL STRATEGIES

This subject will be developed based on:

• Search and organization of information.

• Presentations, articles and others online.

• Didactic exhibition: Online conferences, videos.

• Online tutoring: platform tools, messaging, chat, video conferencing, others.

• Student presentations: Multimedia presentations, videos, others.

• Teamwork.

• Problem-based learning.

• Bibliographic research.

• Debate.

For the learning sessions, the student will have the information available in the virtual classroom:

Syllable of the Subject.

Learning Guide.

Videoconference slides (PPT) in different formats.

Texts or other resources (e-books, magazines, articles, web pages, video class) that are necessary for the development of your class.

SPECIFIC CONSIDERATIONS:

Theoretical/practical class sessions:

The student must have done previous readings of the thematic content before starting each class session.

In the practical sessions, students will be grouped in a number of 10 to 15 students per teacher.

Assignment of one teacher per practice session, at each work table.

THEORETICAL SESSION : The objective is to provide the student with the conceptual theoretical framework of the topic to be

developed according to the syllabic plan, and due to the dynamic nature of the subject it will be dialogued, with the active participation

of the teacher and the students. To do this, the student must previously read or view the topic to be discussed in order to be familiar

with the development of the class. This will start at the EXACT TIME and the syllable must always be carried to carry out the

respective follow-up. In the event that the theoretical class is not taught on the scheduled date, it will be rescheduled.

DIRECTED PRACTICE : Corresponds to the reinforcement and development of procedural skills of the theoretical information given

in the classroom and will be face-to-face. For this, the student will have a technological platform for the practical approach. Students

will be under the permanent attention of a teacher in person for each of these groups. Likewise; These sessions will be held

according to the syllabic schedule and at the EXACT TIME .

SEMINARS : These are presentations given by students on specific topics of interest for their professional training. These holds will

be carried out randomly during the practical session. The teachers responsible for the practice will act as inductors, guides and

integrators of this activity.

DIDACTIC PROCEDURES TO FOLLOW: In order to meet the objectives indicated above, the Expository - Interrogative Method will

be followed in the lectures, while in Practice the Demonstrative method will be followed virtually. RESEARCH: Students, for each

practice group, will make a proposal for a Virtual Event on a topic of interest, which must conclude with a public exhibition, or

alternatively with a publication at the end of the semester.

SUBSTITUTE EXAM
According to the current academic directive; Section 5.18, in section a) states that the student who fails a subject or wishes to

improve his or her promotional average has the right to take a substitute exam, whose grade replaces that of the partial exam or

the final exam, which best suits him/her. favors in the calculation of the promotional average of the subject, in the respective

academic period. The student who takes the substitute exam cannot request its cancellation. Likewise, in section b) it states that

the topic for the substitute exam corresponds to the entire subject. The student has the right to take a substitute exam if his or her

grade is greater than or equal to seven (07) and make the respective fee payments.
 CLASS ATTENDANCE: Students with more than 30% absences from class will be disqualified by the system in the subject.

OTHERS:

• The student who misses any evaluation will have a zero grade . Absence (maximum of 2 days after the absence) to an

evaluation is justified to be taken only by authorization of the School Director.

• There are no make-up exams.

VI RESOURCES AND TEACHING SCENARIOS - LEARNING.

The materials that will be used for the development of the subject are the following:

1. Virtual classroom platform.

2. Digital tools: Google Drive / Google Forms / Others.

VII EVALUATION TECHNIQUES AND INSTRUMENTS

EVALUATION COMPONENTS
PROCESS EVALUATION 1
(EP1) 25%
EXAM I UNIT (EX I) 70%

PRACTICAL EXAM 1 (PRAC 1) 30%

PARTIAL EVALUATION (EVP) 20%

PROCESS EVALUATION 2 (EP2) 30%

EXAM III UNIT (EX III) 50%

PRACTICAL EXAM 2 (PRAC 2) 25%

VIRTUAL EVENT + SEMINARS + RSU (INVESTIG) 25%

FINAL EVALUATION (EVF) 25%

CALCULATION FOR THE FINAL GRADE OF THE SUBJECT OR PROMOTIONAL GRADE (PROMO):
1. First process note (EP1):
- EP1 = EX I + PRAC 1

2. Second process note (EP2):

- EP2 = EX III + PRAC 2 + INVESTIG

PROMOTIONAL NOTE (PROMO)

PROMO = 25%*EP1 + 20%*EVP + 30%*EP2 + 25%*EVF

All evaluations are with a Vigesimal scale

VIII TUTORING AND PEDAGOGICAL SUPPORT STRATEGIES

IX BIBLIOGRAPHY

BASIC BIBLIOGRAPHY

Murray, Rosenthal and Pfaller

MEDICAL MICROBIOLOGY 2017

8va. Edition. Barcelona: ELSEVIER

 FURTHER READING

Madigan, Martinko, Bender, Buckley and Stahl

BROCK. BIOLOGY OF MICROORGANISMS 2015

14va. Edition. Madrid: PEARSON EDUCACIÓN SA.

Ryan KJ and Ray CG

MEDICAL MICROBIOLOGY 2017

6th. Edition. Mexico City: Mac Graw Hill Education.

Bennett JE, Dolin R. and Blaser Mj

MANDELL, DOUGLAS AND BENNETT. INFECTIOUS DISEASES, PRINCIPLES AND PRACTICE. VOLUME 1 AND 2 2015

8va. Edition. Barcelona: ELSEVIER

Bonifaz-Trujillo JA

BASIC MEDICAL MYCOLOGY 2015

5th. Edition. Mexico City: Mac Graw Hill Education.

Vargas Córdova A.

MEDICAL VIROLOGY. 2016

2nd. Edition. Bogotá DC: Editorial El manual Moderno SAS

Avila E.

ANTIBIOTIC RESISTANCE PROFILE OF HELICOBACTER PYLORI ISOLATION IN DYSPEPTICAL PATIENTS

SERVED IN THE HOSPITALS OF TRUJILLO, CHICLAYO AND CAJAMARCA 2017

Master's Thesis. National university of Trujillo

González J., Avila E., Reyna L., Gómez K., Terán A.

IN VITRO EFFECT OF ETHANOLIC EXTRACTS FROM THE FRUIT OF VITIS VINIFERA (GRAPE) AND ANNONA MURICATA

(SOURSOP) ON THE FORMATION OF BIOFILMS OF STREPTOCOCCUS MUTANS ATCC25175 2015

Town Cont. 2015; 26(2):427-440

Terán A., Gonzáles J., Gómez K., Reyna L., and Avila E.

IN VITRO EFFECT OF THE ESSENTIAL OIL OF THE FRUITS OF CAESALPINIA SPINOSA (MOLINA) KUNTZE, TARA, ON THE

VIABILITY OF CROPS OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS 2015

Town Cont. 2015; 26(1):75-87

Avila E.

IDENTIFICATION AND CHARACTERIZATION OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) IN STAFF

OF THE INTENSIVE THERAPY UNITS OF THE REGIONAL TEACHING HOSPITAL OF TRUJILLO, LA LIBERTAD - 2013 2013

Town Cont. 2013; 24(2):343-348

Casquero J., Guevara M., Urcia F., Asmat P., et al.

FREQUENCY OF ASPERGILLOMA IN PATIENTS WITH A HISTORY OF TUBERCULOSIS, HEMPOTYSIS, ABNORMAL

RADIOGRAPHY AND NEGATIVE BACILOSCOPY 2006

Peruvian Journal of Experimental Medicine and Public Health. 2006;23(2):104-109

Asmat P., Huapaya B., Hurtado E.

ISOLATION OF ENTEROHEMORRHAGIC ESCHERICHIA COLI FROM CHILDREN WITH ACUTE DIARRHEA CARE IN THREE

HEALTH FACILITIES IN TRUJILLO 2010

International Scientific Congress of the National Institute of Health. Nov 11-13 2010

González Cabeza J.

CLONING 1998

University of Huánuco Magazine. 1998;1(1):38-40

González Cabeza J.

USE OF CAFFEINE AS AN ANTI-REPAIR OF DNA, IN THE ASSESSMENT OF GENOTOXICITY IN THE CELL CYCLE OF

MERISTEMS OF ALLIUM CEPA 1999

Master's Thesis.

González Cabeza J.

MOLECULAR MICROBIOLOGY. PRACTICE GUIDE OF THE AUTONOMOUS UNIVERSITY OF BARCELONA-SPAIN

2002

UAB

González Cabeza J.

GENOTOXICITY ASSESSMENT 2002

Experimental work. UAB, Faculty of Sciences. Department of Genetics and Microbiology

González Cabeza J.

VIROLOGY PRACTICES. PRACTICE GUIDE OF THE AUTONOMOUS UNIVERSITY OF BARCELONA (UAB) 2003 UAB

González Cabeza J.

STUDY OF THE MECHANISMS OF MUTAGENESIS AND MUTAGENIC POWER OF QUINOLONES 2004

Doctoral Thesis. Autonomous University of Barcelona (UAB)

González Cabeza J.

CLONING OF THE UVRB GENE, MOA OPERON AND REQUIREMENTS OF THE UVRABC COMPLEX DURING MUTAGENESIS

BY QUINOLONES IN SALMONELLA TIPHYMURIUM STRAINS (UVRB AND MOAA-E) 2006 Pueblo Cont. 2006; 17(2)

González Cabeza J. et al.

THE SELECTION OF RESISTANCE TO AND THE MUTAGENCITY OF DIFFERENT FLUOROQUINOLONES IN

STAPHYLOCOCCUS AUREUS AND STREPTOCOCCUS PNEUMONIAE 2005

Journal of European Society of Clinical Microbiology and Infectious Diseases

González J., Araujo A., Avila E., and Chuna P.

MICROBIAL STRUCTURE AND PHYSIOLOGY 2010

1a. Edition. 138 pages

González J., Araujo A., Reyna L., and Chuna P.

MICROBIOLOGY: HISTORY, STRUCTURE, PHYSIOLOGY, METABOLISM, ANTIMICROBIALS, AND PRINCIPLES OF

IMMUNOLOGY 2011

2nd. Edition. Multicopy Publishing. 228 pages

González J., Araujo A., Chuna P. and Terán J.

PRACTICAL FOUNDATIONS OF MICROBIOLOGY 2011

1st. Edition. Multicopy publishing house. 264 pages

González Cabeza J.

BIODIESEL PRODUCTION FROM MICROALGAE SCENEDESMUS SPP. IN PHOTOBIOREACTOR TANK

AGITATED 2013

Town Cont. 2013; 24(2):379-391

González Cabeza J.

DETECTION AND GENOTYPIFICATION OF HUMAN PAPILLOMAVIRUS BY PCR-RFLP IN PATIENTS CARED FOR AT THE

WALTER CRUZ VILCA DISTRITAL HOSPITAL 2016

Town Cont. 2016; 27(2):331-342

González Cabeza J.

DETECTION AND GENOTYPICAL CHARACTERIZATION OF BETA-LACTAMASES FROM UROPATHOGENIC ESCHERICHIA

COLI

BELÉN HOSPITAL DE TRUJILLO DURING JANUARY-APRIL, 2015 2017

Town Cont. 2013; 28(1):57-66

González Cabeza J.

BIOINFORMATICS APPLICATIONS: ORIGIN OF BIOINFORMATICS 2017

Town Cont. 2017; 28(2):373-377