This clinical worksheet provides information on the medication Silver sulfadiazine (Silvadene). It is an anti-infective cream used topically twice daily to prevent and treat wound sepsis in patients with 2nd- and 3rd-degree burns. The medication works by disrupting the bacterial cell membrane and wall. Nursing implications include monitoring for renal and blood abnormalities from systemic absorption as well as educating patients on the purpose and proper application of the medication.
This clinical worksheet provides information on the medication Silver sulfadiazine (Silvadene). It is an anti-infective cream used topically twice daily to prevent and treat wound sepsis in patients with 2nd- and 3rd-degree burns. The medication works by disrupting the bacterial cell membrane and wall. Nursing implications include monitoring for renal and blood abnormalities from systemic absorption as well as educating patients on the purpose and proper application of the medication.
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This clinical worksheet provides information on the medication Silver sulfadiazine (Silvadene). It is an anti-infective cream used topically twice daily to prevent and treat wound sepsis in patients with 2nd- and 3rd-degree burns. The medication works by disrupting the bacterial cell membrane and wall. Nursing implications include monitoring for renal and blood abnormalities from systemic absorption as well as educating patients on the purpose and proper application of the medication.
Copyright:
Attribution Non-Commercial (BY-NC)
Available Formats
Download as DOCX, PDF, TXT or read online from Scribd
Generic Name Trade Name Classification Dose Route Time/frequency
Silver sulfadiazine Silvadene Anti-infectives (topical) inexact topical bid Peak Onset Duration Normal dosage range unknown On contact As long as Apply 1% cream 1-2 times daily in layer 1.5-mm thick applied Why is your patient getting this medication For IV meds, compatibility with IV drips and/or Prevention and treatment of wound sepsis in patients solutions with 2nd- and 3rd-degree burns. N/A
Mechanism of action and indications Nursing Implications (what to focus on)
(Why med ordered) Contraindications/warnings/interactions Studies utilizing radioactive micronized silver Hypersensitivity (cross-sensitivity with sulfonamides may sulfadiazine, electron microscopy, and biochemical occur), Impaired hepatic or renal function. techniques have revealed that the mechanism of Common side effects action of silver sulfadiazine on bacteria differs from No common or life-threatening side effects silver nitrate and sodium sulfadiazine. Silver sulfadiazine acts only on the cell membrane and cell wall to produce its bactericidal effect. Interactions with other patient drugs, OTC or Lab value alterations caused by medicine herbal medicines (ask patient specifically) Monitor renal function studies and CBC periodically when None for this patient applied to large area, because systemic absorption may cause nephritis and reversible leukopenia. Decrease in neutrophil count is greatest 4 days after initiation of therapy; levels usually normalize after 2-3 days. Be sure to teach the patient the following about this medication Explain purpose of medication to patient and family. This medication will not stain skin. Nursing Process- Assessment Assessment Evaluation (Pre-administration assessment) Why would you hold or not give this Check after giving Assess burned tissue for infection med? Prevention and treatment of (purulent discharge, excessive moisture, Hypersensitivity reaction (rash, infection in 2nd- and 3rd- odor, and culture results) and sepsis itching, or burning) at and surrounding degree burns. Therapy is (WBC, fever, or shock) prior to and sites of application. continued until burn is throughout course of therapy. healed or skin graft is performed.