Professional Documents
Culture Documents
Genome
Genome
Human Genome
Double-stranded DNA Complementary nucleotide base pairing
Number of base pairs in human genome: 99.9% bases identical among people 0.1% / 3 millions pairs scattered in separate regions At least 50% known as junk DNA or minisatellites or tandem repeats, not coding for proteins
3 billions
estimated 80,000140,000
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Address ethical, legal and social issues (ELSI) that may arise from the HGP
Human Genome Project 4
risks caused by exposure to mutagenic chemicals and cancer-causing toxins population groups based on female genetic inheritance
Human Genome Project
identify potential suspects whose DNA may match evidence left at crime scenes, identify crime and catastrophe victims, identify endangered and protected species as an aid to wildlife officials (could be used for prosecuting poachers )
Bioprocessing e.g. to create disease-, insect-, and drought-resistant crops, to create healthier, more productive, disease-resistant farm animals, to obtain more nutritious produce
Human Genome Project 6
insurers, employers, courts, schools, adoption agencies , and the military, among others
information
agreement for complex and potentially controversial procedures, use of genetic information in reproductive decision making, and reproductive rights.
Human Genome Project 7
doctors and other health service providers, patients, and the general public in genetic capabilities, scientific limitations, and social risks; and implementation of standards and quality-control measures in testing procedures. regarding human responsibility, free will vs genetic determinism, and concepts of health and disease.
rights (patents , copyrights, and trade secrets) and accessibility of data and materials.
Useful websites
http://www.sanger.ac.uk/HGP/ http://www.ornl.gov/sci/techresources/ Human_Genome/home.shtml http://www.genome.gov/Pages/Educati onKit/index.html http://www.doegenomes.org/ http://www.genome.gov/Pages/Educati onKit/download.html
Human Genome Project 10
Assignment
Discuss among the members of your group for the question about ELSI. Present your findings. Finish the worksheet given.
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