Cortisol, Fixing Imbalances

Elevated Cortisol Levels
What it is, What is causes & How to

Correct it.
The Wellness Center

Dr. Theresa Dale, PhD, CCN, NP
Cortisol
• Cortisol is a hormone that is released when your body and mind
perceive a threat. Its that fight or flight reaction. If you are under
constant stress, the levels of cortisol in your body can start to build
up.
• A mild case of elevated cortisol levels may not even cause any
noticeable symptoms. For this, a blood test is needed. Cortisol levels
can be high for a very long time before any symptoms present
themselves. Cushing's syndrome occurs when the body is exposed to
highly elevated amounts of cortisol, usually over a long period of time.
Cortisol
• Under normal circumstances your body produces more cortisol in the
morning (to fuel energy needs) than in the evening, giving you the
energy that you need to begin your day. In the evening your cortisol
level should drop by approximately 90%.
• Evening is generally the time when the stresses of the day are behind
you, the time when you can relax and unwind. Scientific data is
showing that elevated cortisol levels are becoming more
commonplace.
• Elevated cortisol levels can be related to blood sugar, thyroid
function, estrogen, Elevated cortisol levels may indicate adrenal
fatigue, high levels of stress, adrenal tumors, and Cushing syndrome.
Cortisol is needed
• for nearly all dynamic processes in the body, from blood
pressure regulation and kidney function, to glucose levels and
fat building, muscle building, protein synthesis and immune
function.
• One of cortisol’s more important functions is to act in concert
or synergy with thyroid hormone at the receptor-gene level.
Cortisol makes thyroid work more efficiently. A physiologic
amount of cortisol—not too high and not too low—is very
important for normal thyroid function, which is why a lot of
people who have an imbalance in adrenal cortisol levels usually
have thyroid-like symptoms but normal thyroid hormone levels.
Both thyroid and cortisol
• have to be present in the cells bound to their
respective receptors at normal levels, to efficiently
turn the valve on and get gene expression. So,
when cortisol levels are low, caused by adrenal
exhaustion, thyroid is less efficient at doing its job
of increasing energy and metabolic activity.
• Every cell in the body has receptors for both
cortisol and thyroid and nearly every cellular
process requires optimal functioning of thyroid.
Elevated Cortisol
• Too much cortisol, again caused by the adrenal glands’ response to excessive
stressors, causes the tissues to no longer respond to the thyroid hormone signal.
It creates a condition of thyroid resistance, meaning that thyroid hormone levels
can be normal, but tissues fail to respond as efficiently to the thyroid signal. This
resistance to the thyroid hormone signal caused by high cortisol is not just
restricted to thyroid hormone but applies to all other hormones such as insulin,
progesterone, estrogens, testosterone, and even cortisol itself.
• When cortisol gets too high, you start getting resistance from the hormone
receptors, and it requires more hormones to create the same effect. That’s why
chronic stress, which elevates cortisol levels, makes you feel so rotten—none of
the hormones are allowed to work at optimal levels.
• Insulin resistance is a classic example. It takes more insulin to drive glucose into
the cells when cortisol is high. High cortisol and high insulin, resulting in insulin
resistance, are going to cause you to gain weight around the waist because your
body will store fat there rather than burn it.
Elevated Cortisol
• Insulin resistance is a classic example. It takes
more insulin to drive glucose into the cells
when cortisol is high. High cortisol and high
insulin, resulting in insulin resistance, are
going to cause you to gain weight around the
waist because your body will store fat there
rather than burn it.
When cortisol is high
• the brain also is less sensitive to estrogens. That’s why you can
have a postmenopausal woman with reasonable amounts of
estrogen, but when you put her under a stressor and her cortisol
rises, she’ll get hot flashes, which are a symptom of estrogen
deficiency.
• Elevated Cortisol affects neurotransmitter balance.
• The postmenopausal woman doesn’t have an estrogen
deficiency, the brain sensors have just been altered. If you then
drive the estrogen levels up with supplementation to treat the
hot flashes, she’ll start getting symptoms of estrogen dominance
like weight gain in the hips, water retention, and moodiness. And
the hot flashes usually don’t go away.
Its Proven that HRT or BHRT Doesn’t Work!
• This is precisely why you can’t effectively treat

someone with hormonal imbalance symptoms
such as hot flashes by simply adding what
seems to be the missing hormone, be it
thyroid, progesterone, estrogen or
testosterone. If your cortisol is chronically high
you’ll have overall resistance to your
hormones.
Treatment Proven to Work
• This IS WHY the only treatment documented and
proven to work to effectively to balance high and low
cortisol is our proven NuFem and EndoPure. We have
20,000 before and after salivary tests. Our
complimentary PROGRAM addresses all the issues
that were created by lifestyle, medications, HRT, BHT,
etc.
• Our NuFem hormone rejuvenation system not only
balance cortisol levels, they also balance the entire
feedback loop - Hypothalamus, Pituitary, Adrenal Axis.
Stress is what
• both high and low cortisol have in common. Stress
hits the adrenals and in response they either
collapse in fatigue and do not produce enough
stress hormones, resulting in a functional thyroid
deficiency, or they can go in the other direction
where they’re pouring out cortisol and it’s causing
overall hormone resistance, including thyroid
resistance. Either way, low or high cortisol, and
thyroid hormones become inefficient.
Cortisol helps maintain
• blood glucose levels by activating
gluconeogenesis, the breakdown of tissue
protein to amino acids and then to glucose.
That’s a good thing, but not in excess.
• Too much cortisol, caused by stressors, over a
prolonged period of time, results in excessive
breakdown of all structural tissues of the body
including muscle, bone, skin and brain, causing
accelerated aging.
In bones,
• high cortisol activates nearly every biochemical pathway involved in bone
resorption. Cortisol specifically inhibits osteoblast activity, or bone building; it
suppresses the production of androgens [male hormones] in the gonads
[androgens build bone]; it activates osteoclasts which causes bone to be
resorbed faster; it decreases mineral absorption in the gut, so you won’t be
absorbing the calcium and magnesium you need to build bone; and it increases
renal [kidney] tubule spilling of calcium.
• Calcium supplementation and alendronate-type drugs used to inhibit bone
resorption, such as Fosamax, will always fight a losing battle to high cortisol. I
frequently see women reporting continued bone loss, despite use of
pharmaceutical bone resorption inhibitors, when salivary cortisol levels are very
high.
• Fix the cortisol balance and use Nano Ionic Bone to balance and restore calcium
levels. Ionic form of supplementation means that the supplement is cell-ready
and absorption is 100%.
With saliva testing
• we see that when people have very high cortisol and
low androgens they tend to have bone loss even
when their progesterone and estrogen are normal. I
see the most bone loss in women who have had a
total hysterectomy.
• This is due to cortisol levels that has not been
handled properly. You see possibly using calcium
supplementation that is toxic instead of our Nano
Ionic Bone formula causes general toxicity and
severe adrenal stress
Cortisol is released
• from the adrenal glands in a rhythmic pattern
throughout the day. It’s high in the morning,
which energizes you. If you don’t have enough
cortisol in the morning you have a hard time
getting out of bed. It’s at its lowest levels at
two a.m. when melatonin is high. Melatonin
and cortisol are inversely related, so when
cortisol is down and melatonin is up you’re
regenerating your body.
When your cortisol stays high
• you also won’t produce enough growth hormone or
thyroid-stimulating hormone, which are important
anabolic [tissue building] hormones. This is why a good
sleep is so important. People with high salivary night
cortisol levels are usually complaining of sleep problems.
• To balance Melatonin, Cortisol and Hormones Use NuFem
and EndoPure along with BioAge Reverse for HGH, Thyro
T3 Rescue for Thyroid and Parathyroid. A Whole Body
Deep Cleanse is a foundational system of healing cortisol
levels, digestion, and detoxification for every patient.
• The potential role of excessive cortisol
induced by HPA hyperfunction in the
pathogenesis of depression.
• By Peter E Stokes
Prolonged hypothalamic-pituitary-
adrenocortical (HPA)
• axis overactivity occurs at all levels of this axis during stress in normals and
some depressed patients. This can induce enlargement of the pituitary and
adrenals.
• Various reports showed that cortisol can affect mood and behavior, and disrupt
memory and recall. The integrity of the hippocampus is essential for memory
function and, via the high density of its cortisol receptors, cortisol induced
inhibitory feedback to the HPA axis. Animal data suggest that over time aging
and stress can permanently downregulate hippocampal cell receptors, produce
chronic hippocampal inflammation (astroglial), and kill cells.
• Cushing's syndrome patients (high cortisol) show diminished hippocampal size
and verbal recall inversely related to cortisol levels. All the above is consistent
with the ‘cascade hypothesis’ of cortisol induced hippocampal damage with
resultant diminished inhibition to HPA hyperactivity in a circular manner.
Continued
• High cortisol is associated with altered
neurotransmitter function, e.g., diminished
brain serotonin synthesis, low CSF 5HIAA, and
increased noradrenergic activity. ( Low
cerebrospinal fluid 5-hydroxyindoleacetic acid
concentration differentiates impulsive from
nonimpulsive violent behavior.)
– How to fix low CSF 5HIAA?
– Answer: NeuroBalance Pro and HGP Formula.
Tech Support
• What are the optimal Reference ranges for
hormones and cortisols.
• We offer you a complimentary program which
is equivalent to tech support. We review the
case history and the results and write a
custom program for your patient.
• In addition, if you want live tech support, just
call Theresa Dale.
• references
• Dr. David Zava
• Peter E Stokes

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Elevated Cortisol Levels

What it is, What is causes & How to

The Wellness Center

• This is precisely why you can’t effectively treat

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