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Diabetic Neuropathy
Diabetic Neuropathy
• Symptoms
• Treatments
• Research
Diabetes Mellitus and Neuropathy*
disease or dysfunction of one or more peripheral nerves, typically
causing numbness or weakness.
Diabetes Mellitus
A metabolic disease, affects how our cells
(don’t) utilize glucose, our body’s primary
energy source
Type 1 “Autoimmune” Diabetes Mellitus the
pancreatic islets do not produce enough
Insulin to manage blood glucose
Type 2,formerly “acquired” Diabetes Mellitus
-cells become resistant to high blood glucose
concentration, no longer respond to presence
of Insulin
Long term deprivation of energy gradually
degrades and damages all cells and tissues
Applied Concepts
The combined effect of mesenchymal stem cells and resveratrol on type 1 diabetic neuropathy
study demonstrated that mesenchymal stem cells (MSCs) or resveratrol (RSV) may improve diabetic
hyperglycemia and neuropathy. The aim of the present study was to investigate the combined effect of
MSCs and RSV on DN.
Compared with the diabetic control group, the blood glucose of mice in the MSCs, RSV (until day 35)
and MSCs + RSV groups were decreased following therapy (P<0.05). Blood glucose in the MSCs and
MSCs + RSV group reached a normal level at day 14, and this was maintained until the end of the
experiment; no significant differences were identified in the blood glucose levels between the two
groups.
Evaluation of various risk factors associated with multidrug-resistant organisms isolated from diabetic foot
ulcer patients
Diabetic foot ulcer patients are often infected with multidrug resistant organisms (MDRO) due to
inappropriate antibiotic treatment, chronic course of the wound, frequent hospital admission,
neuropathy, nephropathy, and peripheral vascular disease. Furthermore, due to peripheral arterial
disease, there is poor penetration of antibiotics into the lower limb tissue, thereby promoting selection
of resistant bacterial strains.
Conclusion
Multiple Choice
BY CURRENT MEDICAL TREATMENTS.
A. TRUE
B. FALSE.
Questions: 3. DIABETIC NEUROPATHY
A. DAMAGES TISSUES NOURISHING AND SUPPORTING
NERVES, LEADING TO GRADUAL DEGENERATION OF
SKIN, MUSCLE AND NERVOUS TISSUE.
B. REDUCES THE AVAILABILITY OF GLUCOSE REQUIRED
FOR NERVES TO PERFORM THEIR FUNCTION.
C. BOTH A AND B.
D. NONE OF THE ABOVE.