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Applications OF Analytical Chemistry in Forensics: Maimoona Saeed PCHEM01193002 Semester 2
Applications OF Analytical Chemistry in Forensics: Maimoona Saeed PCHEM01193002 Semester 2
OF
ANALYTICAL
CHEMISTRY
IN FORENSICS
MAIMOONA SAEED
PCHEM01193002
SEMESTER 2
Characterization of One Pot methamphetamine
laboratories using GC-MS and LC-MS/MS
Methamphetamine (contracted
from N-methylamphetamine) is a
potent central nervous
system(CNS) stimulant that is
mainly used as a recreational drug
and less commonly as a second-
line treatment for attention deficit
hyperactivity disorder and obesity
INGREDIENTS USED TO “COOK” METH
IN ONE POT:
A simpler, less expensive and faster
Alcohol Hydrochloric/muriatic acid
method of making meth is increasing in
Anhydrous ammonia-
fertilizer
Hydrogen peroxide popularity. The smaller batch known as
Antifreeze Iodine crystals the one pot, shake and bake, or 2L bottle
Battery acid Lead acetate method uses a 2-liter plastic bottle. Cold
Benzene Lighter fluid medicine and noxious chemicals are added
Charcoal lighter fluid Lithium from batteries to the bottle and shaken. No flame is
Diet aids/ephedrine Lye-sodium hydroxide needed.
Di-ethyl ether – camp stove Nail polish remover – This 2-liter method produces powerful
fuel acetone explosions, intense fires and releases toxic
Energy boosters
OTC cold waste. Even small mistakes in the process,
medicine/pseudoephedrine
such as removing the cap too soon or
Ethyl ether – starter fluid Paint thinner
allowing water into the mix, can cause an
Red phosphorus –
Freon
matches/flares explosion.
Gasoline Sulfuric acid – drain cleaner
Techniques used for its
characterization:
Methamphetamine was prepared by one pot method.
The solid waste (sludge), the liquid waste (post-salt solvent), and the product salts
were collected and analyzed for reaction byproducts.
Liquid-liquid extraction (LLE) was performed on the post-salt solvents to prepare
the samples for GC-MS analysis.
For LC-MS analysis, the post-salt solvent was diluted in deionized water.
Liquid-liquid extraction
(LLE)
GC-MS
LC-MS