Neoplastic Diseases: P. Manyau School of Pharmacy University of Zimbabwe
Neoplastic Diseases: P. Manyau School of Pharmacy University of Zimbabwe
P. Manyau
School of Pharmacy
University of Zimbabwe
Objectives
• Define cancer
• Cell cycle
• Discuss mechanisms of Carcinogenesis
• Chemical carcinogens
• Malignancies associated with infection
• Oncogenes and tumour suppressor genes
• Tumour growth
• Tumour characteristics
• Screening, diagnosis
• Treatment modalities
• chemotherapy
The Balancing Act
• Growth, stasis and degeneration
• Genetic mechanisms underlying
factor
• Homeostatic functions that
regulate
• Which cell type is replicated
• Time of cell death
• With age this balance is not
easily maintained
Cancer
• Cancer is a group of more than
100 different diseases
• It is characterised by
uncontrolled cell replication,
local tissue invasion and distant
metastases.