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Gene Mutation: Presentated By: - Abida Khan - Shumaila Gull - Mehwish Rahman
Gene Mutation: Presentated By: - Abida Khan - Shumaila Gull - Mehwish Rahman
Presentated by:
•Abida khan
•Shumaila Gull
•Mehwish Rahman
Topic to be covered:
• What is gene mutation?
• How common are mutations?
• If I have that many mutations, why do not I
look weird?
• How do a mutation affect a population?
• Causes of gene mutation
• Types of mutation
• conclusion
What is gene mutation?
• framshift
Point mutation
• A point mutation or substitution is a genetic
mutation where a single nucleotide base is
changed.
• There are three types of point mutation:
1. Silent
2. Miss sense
3. Non sense
Point mutation types
substitution
Frame shift mutation
• Also know as frame error
• A frameshift mutation is a
genetic mutation caused by a deletion or
insertion in a DNA sequence that shifts the
way the sequence is read. ...
Therefore, frameshift mutations result in
abnormal protein products with an incorrect
amino acid sequence that can be either longer
or shorter than the normal protein.
Frame shift muation
Classification of mutation on basis of affected
cell:
On the basis of the cell affected mutation can be
divided as:
• Somatic cell mutation: when there is a change
in DNA sequence of a somatic or non-
reproductive cell.
• Germinal cell mutation: when there is
mutation in the reproductive cells like gonads.