Traditional Biotechnology

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TRADITIONAL

BIOTECHNOLOGY
• Early examples of biotechnology include
breeding animals and crops, and using
microorganisms to make cheese, yoghurt, bread,
beer and wine.
• The earliest example of biotechnology is the domestication of
plants and animals.
• Domestication began over 10,000 years ago when our ancestors
started keeping plants as a reliable source of food.
• Rice, barley and wheat were among the first domesticated plants.
Wild animals were tamed to provide milk or meat or help with
ploughing or guarding the farm.
• The dog, sheep and goat are thought to be among the first animals
that were domesticated.
• Our early ancestors used microorganisms to make cheese, yoghurt and
bread, alcoholic drinks like beer and wine.
• All of these foods and drinks are made by fermentation.
• Fermentation is a process in which sugars are transformed into a new
product through chemical reactions carried out by microorganisms
(yeast, moulds and bacteria)
• The products generated from fermentation affect the nature of the food
that the microorganism is in – carbon dioxide causes bread to rise,
lactic acid makes yoghurt sour, and alcohol is produced in the
formation of beer and wine.
• Louis Pasteur first described the scientific basis for
fermentation in the late 1800s.
• Pasteur’s hypothesis, called the germ theory, showed the
existence of microorganisms and their effect on fermentation.
• Pasteur’s work gave birth to many branches of science.
Louis Pasteur

Louis Pasteur (1822-1895) was a


French chemist who made several
key discoveries. He proved that
infectious diseases were caused by
microorganisms, developed the first
vaccines and invented pasteurisation.
Traditional medicines
• Some traditional medicines also used organisms or parts of organisms. For
example, the ancient Egyptians used honey for respiratory infections and as an
ointment for wounds. Honey is a natural antibiotic, killing the germs in wounds.
• By about 600 BC, the Chinese were using mouldy soybean curds to treat boils.
Similarly, Ukrainian peasants were using mouldy cheese to treat infected wounds.
The moulds released natural antibiotics that killed bacteria and prevented the
spread of infection.
• Despite these natural treatments, it wasn’t until 1928 that Alexander Fleming first
extracted penicillin – the first antibiotic – from mould.
Examples of selective breeding
• Corn is a dramatic example of a plant that has been
enhanced by selective breeding to become a better source of
food.
• Early teosinte plants (about 5000 BC) had small cobs with
few kernels, but by 1500 AD, the corn cobs were more than
5 times the size and packed full of sweet, juicy kernels.
Dog breeds
• There are more than 100 breeds of dog, all resulting from selective breeding.
• Dogs were bred for specific jobs and to enhance traits such as size, shape, agility
and colour, resulting in breeds from the tiny Chihuahua to the Great Dane.
The discovery of genes
A monk named Gregor Mendel identified genes as the unit of inheritance in
1865. It took another 90 years of research before the structure of DNA was
described in 1953.
This discovery was the beginning of modern biotechnology.

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