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How long does paracetamol take to work?

WHEN in pain, you may be wondering how long it will take for the paracetamol to kick in.

The over-the-counter painkillers work for most common ailments, from headaches to period cramps.

Paracetamol can take up to an hour to work
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Paracetamol can take up to an hour to workCredit: Alamy

Once you take a standard dose, it can take anything up to an hour to work, the NHS says.

But it may be as little as half an hour.

The effects can last several hours, with a peak of around two hours from digestion. 

A usual dose is one or two 500mg tablets.

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You don’t need to worry about when you last ate or drank something when taking paracetamol.

And it’s safe to drink a little amount of alcohol with the painkiller, the NHS says.

However, some research has suggested what you drink when popping a pill could affect how fast it's digested.

Once a medicine is swallowed, it is broken down by stomach acids before it passes through the liver and then enters the bloodstream.

Complete guide to taking paracetamol

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The researchers said that “gastric emptying” - the process of something moving from the stomach to the small intestine to become waste - normally takes around 15 minutes without food.

But common drinks - such as orange juice and Coca-cola - can slow the breakdown of pills, results of lab-controlled experiments published in the Saudi Pharmaceutical Journal showed.

Experts said you should only consume a glass of water when taking meds like paracetamol or ibuprofen to get the full effect. 

If you are taking paracetamol all day, doses should be spread out with four hours in between.

You should take no more than eight 500mg tablets (four doses) per 24 hours.

The NHS website states: "Overdosing on paracetamol can cause serious side effects. Do not be tempted to increase the dose or to take a double dose if your pain is very bad."

The medicine is available in tablet form, which you can swallow with water.

For those who struggle to swallow whole tablets, paracetamol is also available in syrup form or as a soluble tablet.

It is important to read the guidelines on the packaging and to consult with your GP regarding any medications you are taking.

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