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  The Spruce
The main dish casserole is usually a one-pot meal―an easy and convenient way to prepare a family meal. Casseroles came to popularity in the 1950s when casserole dishes were first available to home cooks.Â
Casseroles are often made with a binder―usually a thickened sauce or condensed soup―to hold the ingredients together. While a topping isn't essential, it can add a nice crunchy texture to a dish. Shredded cheese, toasted nuts, French fried onions, buttered bread crumbs, or cracker crumbs are a few popular topping choices. Â
If you're looking for an easy oven-baked casserole, you can't go wrong with one of these popular recipes!
Ritzy Chicken Casserole
The Spruce
Buttered Ritz cracker crumbs top this delicious ritzy chicken casserole. Save time with a rotisserie chicken or packaged roasted chicken strips. The fact that the casserole contains only six ingredients makes it even more appealing!
Burrito Casserole
The Spruce / Diana Rattray
Tex-Mex flavors abound in this fabulous burrito casserole! It's made with layers of seasoned ground beef and refried beans, cheese, and tortillas. To make dinnertime even easier, cook ground meat in advance and store it in the freezer for whenever you need it for a recipe.
Instant Pot Mac and Cheese
The Spruce / Diana Rattray
This Instant Pot macaroni and cheese dish is not only rich and creamy—it is also quick and easy! The Instant Pot pressure cooker makes mac and cheese in just a few minutes. Feel free to top it with some buttered breadcrumbs and pop it under the broiler for a minute or two.
Creamy Ham and Spaghetti Bake With Peas
The Spruce / Diana Rattray
Ham and peas team up in this creamy ham and spaghetti bake with peas. Parmesan cheese tops this easy casserole.
Trying to figure out what else to do with your leftover ham? Look at our
top leftover ham recipes to provide some inspiration!Continue to 5 of 48 belowClassic Instant Pot Shepherd's Pie
The Spruce / Diana Rattray
This classic Instant Pot shepherd's pie is almost entirely cooked in the Instant Pot, which makes it incredibly quick and easy. Pop it under the broiler for a minute to brown the mashed potato topping.
Rich and Creamy Macaroni and Cheese Bake
The Spruce / Diana Rattray
Who doesn't love a comforting rich and creamy macaroni and cheese bake? This creamy version will please everyone in the family.
Corned Beef and Cabbage Casserole
The Spruce / Diana Rattray
Have you run out of ideas for that leftover corned beef? Here's a 7-ingredient corned beef and cabbage casserole. Throw it together, pop it in the oven, and enjoy your free time.
Baked Ziti With Ground Beef and Italian Sausage
The Spruce
A delicious baked ziti with ground beef and Italian sausage features ricotta cheese and cooked ziti pasta for a fabulous cheese-topped casserole.
Continue to 9 of 48 belowChicken Pot Pie
The Spruce / Diana Rattray
A simple recipe for homemade biscuits makes a fabulous topping for this chicken pot pie. The biscuit dough is patted out and then cut into squares. There's no rolling (or re-rolling) required!
Easy Cube Steak Casserole
The Spruce / Diana Rattray
This easy cube steak casserole is a fine example of what you can do with budget-friendly cuts of beef.
Loaded Pizza Pasta Casserole
The Spruce / Diana Mocanu
If you're craving pizza, but don't want to make a crust, try this hearty loaded pizza pasta casserole. The combination of pizza sauce, ground beef, pepperoni, and your favorite toppings makes this dish a meal even the pickiest family members will enjoy.
Unstuffed Peppers Casserole
The Spruce / Diana Rattray
This hot dish of unstuffed peppers casserole is a great way to enjoy the flavors of stuffed peppers. Use a combination of colorful bell peppers, rice, ground beef, and tomatoes and you are set for the evening!
Continue to 13 of 48 belowClassic Tuna Noodle Casserole
​The Spruce / Diana ChistrugaÂ
This classic tuna noodle casserole is always a family favorite. This familiar version contains noodles, condensed soup, peas, and cheese. The browned breadcrumb topping adds crunch and texture.
Shrimp and Rice Casserole
The Spruce / Diana Rattray
You might not think of shrimp for a casserole, but this one will change your mind. Garlic and minced shallots flavor the rice mixture in this easy shrimp and rice casserole dish.
Creamy Turkey Noodle Casserole
The Spruce
A basic medium white sauce brings this creamy turkey noodle casserole together. The dish bakes to golden perfection with a shredded cheddar cheese topping. It can be made with chicken as well, if that's what you have on hand (or prefer).
Crock Pot Potato and Ham Casserole
The Spruce / Diana Rattray
This crock pot potato and ham casserole recipe is made with ham, potatoes, onion, cheddar cheese, and condensed soup. It's a very easy preparation. Just slice the potatoes and onions and layer everything in the slow cooker. Mix the soups and milk together and pour over the casserole.
Continue to 17 of 48 belowBudget-Friendly Cottage Pie
The Spruce / Diana Rattray
Use your leftover roast beef and mashed potatoes to make this budget-friendly cottage pie.
Chicken a la King Casserole
The Spruce
This chicken a la King casserole is a one-dish meal with chicken a la king flavors. The dish comes together with a creamy homemade sauce, celery, and pimientos. Yum!
Mexican Enchiladas
Leah Maroney
This recipe from Central Mexico shows you how to make Mexican enchiladas with your choice of filling, whether it's meat, sautéed veggies, cheese, or a combination. You can make your own enchilada sauce or use store-bought for a quick meal.
Easy Pork and Noodle Bake
The Spruce / Diana Rattray
If you have leftover roasted pork, use it to make this tasty easy pork and noodle bake. Serve this one-dish meal with a tossed salad and crusty French bread.
Continue to 21 of 48 belowSpaghetti Casserole With Ground Beef and Cheese
 The Spruce
Here's yet another excellent pasta bake with ground beef. You'll make this spaghetti casserole with ground beef and cheese again and again. Mozzarella and Parmesan cheeses top it off. This spaghetti pie is a similar preparation.
Chicken Casserole With Potato Chip Topping
The Spruce / Diana Rattray
A potato chip topping adds crunchy flavor to this easy chicken casserole with potato chip topping. It's similar to a hot chicken salad, made with mayonnaise, sour cream, and condensed soup sauce.
Penne Bake With Ham and Peas
The Spruce / Diana Rattray
This is a great way to use leftover ham, and it's a delicious combination of flavors. The cheddar cheese sauce is mixed with cooked penne, diced ham, peas, and seasonings to make a tasty casserole, baked to perfection with a buttery crumb topping. Serve this flavorful penne bake with ham and peas with a tossed salad for a complete and satisfying meal.
Beans and Hot Dogs Casserole
The Spruce / Diana Rattray
A cheesy biscuit topping gussies up this beans and hot dogs casserole. The baked beans get great flavor from barbecue sauce and some chopped vegetables along with mustard and brown sugar. Sliced hot dogs make these doctored beans a hearty one-dish meal.
Continue to 25 of 48 belowHam Pot Pie
Elaine Lemm
Pot pie isn't just for chicken. This recipe using leftover ham has all of the familiar pot pie ingredients and flavors but takes full advantage of that extra ham from the holidays. A mixture of vegetables, including carrots, are combined with the ham and a white sauce and baked in a puff pastry until golden brown.
Chicken Quiche
 Leah Maroney
For those who love breakfast for dinner, this chicken quiche is sure to please. Rotisserie chicken, Gruyere cheese, onion, and parsley are combined with eggs and cream and poured into a homemade crust. Baked in a springform pan, this quiche is easy to cut and pretty to look at.
Chicken Tamale Pie
 Anita Schecter
All of the flavors and textures of a chicken tamale are baked into this easy casserole. A mixture of onion, shredded cooked chicken, black beans, salsa, and taco seasoning is topped with a homemade cornbread batter studded with corn, cheddar, and cilantro. The tamale pie is baked until golden brown and served with sour cream and avocado.
Crescent Beef Stroganoff Bake
The Spruce / Diana Rattray
Here's another casserole that gets a helping hand from convenience food. Crescent roll dough forms the crust for this easy crescent beef stroganoff bake.
Continue to 29 of 48 belowDorito Chicken Casserole
The Spruce
Crushed Dorito chips form the crust and topping for this easy Dorito chicken casserole. The chicken teams up with condensed cream of chicken soup and sour cream. The cheese topping finishes the dish perfectly.
You can even use a can of tomatoes with green chili peppers (e.g., Ro-Tel) to spice things up!Â
Tex-Mex Beef and Biscuit Casserole
Diana Rattray Serve this easy one-dish Tex-Mex beef and biscuit casserole with a tossed green salad or sliced fresh tomatoes and cucumbers for a tasty family dinner.
Beefy Nacho Casserole
The Spruce / Diana Rattray
Layers of tortilla chips, cheese, beef, beans, taco sauce, and salsa make this a satisfying all-in-one main dish. Taco seasoning gives the ground beef Tex-Mex flavor for this beefy nacho casserole.
Pork Chop and Rice Casserole
The Spruce / Diana Rattray
This pork chop and rice casserole​ recipe is an easy baked one-dish meal your family will love. The pork chops are browned and then combined with the vegetables and the easy gravy sauce mixture over the rice. Add some steamed vegetables or spinach to the rice before baking for extra color and flavor.
Continue to 33 of 48 belowChicken and Dressing Casserole
The Spruce / Diana Chistruga
Chicken and dressing casserole brings the flavors of the fall season to any Tuesday night family dinner, without hours of prep and cooking. Just combine the ingredients and pop it in the oven to bake. The cheese topping adds crunchy appeal, but you can easily omit it.
Beef Enchilada Casserole
The Spruce / Diana Rattray
This tasty beef enchilada casserole will surely become a family favorite. With browned ground beef, chili peppers, tortilla chips, and cheese, this is an excellent casserole to bake for a family meal.
Tuna Tetrazzini
The Spruce / Diana Rattray
Tuna and spaghetti team up with mushrooms and Parmesan cheese in this tuna tetrazzini recipe. It's a whole meal in one pot and can be prepared a day in advance, making it a convenient and tasty dish for a busy day.
Southwestern-Style Beef and Potato Bake
The Spruce / Diana Rattray
Southwestern seasonings make this a flavorful Southwestern-style beef and potato bake a dish the whole family will enjoy.
Prepare the casserole earlier in the day and refrigerate until it's time to bake.
Continue to 37 of 48 belowEasy Scalloped Oysters With Cracker Crumbs
The Picture Pantry / Alloy / Getty Images
This easy scalloped oysters with cracker crumbs recipe is not only easy; it's elegant enough for a special occasion. Serve this oyster bake with baked potatoes or rice and a green vegetable.
Ground Beef and Cabbage Casserole
The Spruce
Serve this tasty ground beef and cabbage casserole with mashed potatoes or rice if you'd like a starch. For a low-carb option, serve it with a simple tossed salad or slaw.
Macaroni and Cheese With Sausage
The Spruce / Diana Rattray
Browned sausage and sliced tomatoes help to make this creamy, delicious macaroni and cheese with sausage a hearty main dish. The flavorful casserole is made with pork sausage, chopped vegetables, and a homemade cheese sauce. It's topped with a buttered bread crumb topping and baked to perfection.
Southern-Style Chicken Casserole
The Spruce / Diana Rattray
This Southern-style chicken casserole starts with a cut-up chicken, but leftover chicken or turkey or the meat from a plump rotisserie chicken are excellent alternatives. Vegetables include corn and green beans.
Continue to 41 of 48 belowLow-Carb Chicken and Cauliflower Casserole
The Spruce
Cauliflower takes the place of rice in this tasty low-carb chicken and cauliflower casserole. The one-pot dish makes the perfect meal for anyone watching their carbs. A little cream, some cheddar cheese, and a variety of herbs jazz the casserole up and give it great flavor.
Easy Chicken and Penne Casserole
The Spruce / Diana Rattray
Feel free to make this easy chicken and penne casserole with macaroni or a similar pasta. It's a simple preparation with frozen mixed vegetables, condensed soup, sour cream, and Parmesan cheese.
Easy Chicken and Broccoli Casserole
The Spruce / Diana Rattray
This easy chicken and broccoli casserole is a snap to prepare and bake. Serve this dish with a tossed salad or fresh sliced tomatoes.
Chili Nacho Casserole With Ground Beef and Beans
The Spruce / Diana Rattray
This Chili Nacho Casserole is a well-spiced combination of ground beef, chopped vegetables, cheese, tomatoes, and pinto beans. Tortilla chips are layered with the ground beef mixture.
If you like heat, use pepper jack cheese and add some finely chopped jalapeño or serrano peppers to the beef mixture. Or add some cayenne pepper.
Continue to 45 of 48 belowChicken Enchilada Casserole
Brian Hagiwara / Getty Images
This tasty, popular chicken enchilada casserole recipe is made with sour cream, diced chicken, mushrooms, peppers, tortillas, cheese, and seasonings. Start this Central Mexico-inspired casserole about 1 hour before serving time. The enchiladas are baked on a layer of sour cream and topped shredded cheese.
4-Ingredient Tater Tot Casserole
The Spruce / Diana Rattray
This flavorful 4-ingredient tater tot casserole is easy to prepare and cook in the slow cooker or in the oven. Use frozen mixed vegetables or a blend of peas and carrots, and sauté 1 cup of chopped onion with the ground beef if you like.
Homemade Chicken and Biscuits Casserole
 The Spruce
Quick made-from-scratch biscuits make up the topping for this homemade chicken and biscuits casserole. Feel free to use ready-made frozen or refrigerated biscuits in this recipe.
Spicy Sausage and Penne Casserole
The Spruce / Diana Rattray
Sliced andouille sausage, bell peppers, and some spicy Cajun seasoning gives this spicy sausage and penne casserole its Louisiana flavor.