Articles by OLAW Staff and References

Disclaimer:
OLAW develops and monitors, as well as exercises compliance oversight relative to the Public Health Service Policy on Humane Care and Use of Laboratory Animals (the "PHS Policy"). One of OLAW's primary functions is to advise awarding units and awardee institutions concerning the implementation of the PHS Policy. OLAW often provides this advice by responding to policy-related questions submitted by such units and institutions. The following Articles provide guidance that represents OLAW's current thinking on these topics. This guidance is based on OLAW's experience with the subject matter and draws on best practices followed by the biomedical community regarding the use of research animals. Unless specific statutory or regulatory requirements are cited, the Articles should be viewed as recommendations in that an institution may use an alternative approach if the approach satisfies the requirements of the PHS Policy.

Articles by OLAW Staff

A1  ILAR News 1991; 33(4):68-70. The PHS Responds to Commonly Asked Questions.
A2 ILAR News 1993; 35(3-4):47-49. FAQs about the PHS Policy on Humane Care and Use of Laboratory Animals.
A3 Lab Animal 1994; 23(8):28-29. Compliance at the Institutional Level.
A4 Lab Animal 1995; 24(9):24-26. FAQs about the PHS Policy on Humane Care and Use of Laboratory Animals.
A5 ILAR Journal 1995; 37(4):190-19. Use of Electronic Communications for IACUC Functions.
A6 Contemporary Topics 1996; 35(5):53-56. Model for Performing Institutional Animal Care and Use Committee: Continuing Review of Animal Research.
A7  Contemporary Topics 1997; 36(2):47-50. FAQs about the PHS Policy on Humane Care and Use of Laboratory Animals.
A8 Lab Animal 2000; 29(5):32-37 (PDF). OLAW and APHIS: Common Areas of Noncompliance.
A9  Lab Animal 2002; 31(8):27-30. Disaster Recovery: "Who ya gonna call?”
A10 Lab Animal 2002; 31(9):28-31. Correct Conduct of Full-Committee and Designated Member Protocol Reviews.
A11 Lab Animal 2003; 32(9):33-36. Frequently Asked Questions About the Public Health Service Policy on Humane Care and Use of Laboratory Animals.
A12 Lab Animal 2007; 36(10):40-49 (PDF - 165 KB). Considerations for determining optimal mouse caging density. Disclaimer: The views expressed in "Regulatory Considerations" represent the position of OLAW/NIH, but the remainder of the contributions in this article does not represent official support or an endorsement by NIH or any government agency.
A13 Lab Animal 2009; 38(2):45 (PDF - 112 KB). Reply to ‘Protocol deviations revisited’.
A14 PI eAlert 2009; No. 6 (PDF - 299 KB). Animal Welfare: Lab Rat O.K. as Pet?
A15 Lab Animal eAlert 2010; No. 6 (PDF - 334 KB). What is Protocol for Reporting an Animal-Research Project Exceeding Its Expiration Date?
A16 Lab Animal eAlert 2010; No. 13 (PDF - 236 KB). Making Charges to Grants During an Expiration Period.
A17 PI eAlert 2010; No. 8 (PDF - 322 KB). How Can I Prepare My Animal-Research Lab for an Earthquake?
A18PI eAlert 2010; Jul (PDF - 415 KB). Was McGill’s “Mouse Pain” Study Compliant With Lab Animal Welfare?
A19 Lab Animal eAlert 2010; No. 17 (PDF - 336 KB). Is a laparoscopic serial liver biopsy considered ‘major’ animal surgery?
A20 ILAR Journal 2014; 54(3):324-328 (PDF - 384 KB). What Investigators Need to Know About the Use of Animals.
A21 Zebrafish 2016; 13(6):1-2 (PDF - 83 KB). Office of Laboratory Animal Welfare Comments: Hatching Fish - When should animal tracking begin?
A22 Lab Animal 2017; 46(06) (PDF - 496 KB). Adverse events at research facilities. Addendum: Data Summary (PDF - 92 KB)
A23 Lab Animal 2017; 46(07) (PDF - 476 KB). Tough decisions about protocol review.
A24 JAALAS 2018; 57(02) (PDF - 332 KB). Contribution of the Breadth and Depth of IACUC Membership to Experimental Design as a Factor in Research Reproducibility.
A25 Lab Animal 2019; 48(01) (PDF - 742 KB). Reply to "Clarification on a contradiction"
A26 Lab Animal 2020; 49(05) (PDF - 505 KB). A Word from OLAW: COVID-19 guidance
A27 Laboratory Animal Science Professional 2020; 8(4) (PDF - 1.23 MB). Maintaining Compliance in Unprecedented Times: Flexibilities for Compliance with the PHS Policy During the COVID-19 Pandemic. This article appeared in the AALAS membership magazine, Laboratory Animal Science Professional, July - August 2020, and is reprinted by permission. 
A28 Laboratory Animal Science Professional 2020; 8(6) (PDF - 798.11 KB). Veterinary Staffing Shortages and Potential Solutions During the COVID-19 Pandemic. This article appeared in the AALAS membership magazine, Laboratory Animal Science Professional, November - December 2020, and is reprinted by permission. 

 

References

Dear Colleague Letters
D1 May 21, 1990: Use of Expedited Protocol Review Procedures by IACUCs
D2  January 11, 1994: Internal Distribution of Animal Welfare Assurances
D4 March 8, 1995: Sources of Custom Antibody
D5 June 2, 1997: Maintenance of Properly Constituted IACUCs
D6 November 17, 1997: Production of Monoclonal Antibodies Using Mouse Ascites Method

 

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