Orhan Pelinkovic's Reviews > Who We Are and How We Got Here: Ancient DNA and the New Science of the Human Past

Who We Are and How We Got Here by David  Reich
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bookshelves: science, history, genetics, human-evolution, biological-evolution, biology

The idea of an existence of a pure human race is scientifically dead.

Geneticist, David Reich, discovers through the process of whole-genome sequencing that modern humans are a mixture of a variety of human species, where forty thousand years ago our planet was inhabited by multiple groups of archaic humans that were physically different.

Comparing ancient to modern human DNA, Reich finds that the non-African genome, fifty thousand years ago, which was a direct ancestor of modern humans, had almost 5 percent of Neanderthal origin, while non-African genomes today consist of nearly 2 percent of Neanderthal origin. Hence, Neanderthals and the archaic human interbred. This depletion of the Neanderthal genes is accomplished by natural selection, at the expense of the Neanderthals DNA, and perhaps due to the high infertility of this hybrid. A similar history is shared in Asia and Oceania with the Denisovans, where Neanderthals and Denisovans are cousins. With all these findings, can we conclude that modern humans are to some degree biologically different?

Reich's laboratory was able to trace through analyzing the ancient DNA that the people of the Yamnaya culture from the Eurasian Steppe around five thousand years ago migrated to Europe and to a significant degree replaced the majority of the then existing European population. Reich further hypothesizes that this could be evidence why the Northern European languages spoken today are so closely kindred i.e. as a consequence of the spread of a new culture at the same time.

Genomic data also traces that the descendants of Indians today are a mixture of ancestral people of West Eurasia and South and East Asia and that the spreading of the Yamnaya five thousand years ago could offer a clue on how these two regions and their languages are a part of the same Indo-European language family. What was also fascinating is that an Ancient North Eurasian population genetically contributes one-third of their ancestry of present-day Native Americans, while the natives of the Amazon share ancestry with the indigenous people of Australia, New Guinea, and Andaman.

Who We Are and How We Got Here (2018) reconstruct events of the human past that reveals the history of humankind's movements, interbreeding, and transformations, replacement, and extinction of populations. David Reich in my opinion is not quite the writer and storyteller as Siddhartha Mukherjee, hence, the narrative is not as compelling as it is in Mukherjee's The Gene: An Intimate History. On the other hand, Reich is a heavyweight in his field and his work has and will have a great impact on the future work of archaeologists, anthropologists, and linguists. I have been meaning to read this book for some time now, but reading Sense of History's excellent review of the book triggered me to buy and read it, and I am glad I did.
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Reading Progress

July 8, 2020 – Shelved
July 8, 2020 – Shelved as: to-read
July 27, 2020 – Shelved as: science
October 12, 2020 – Shelved as: history
January 19, 2021 – Shelved as: genetics
January 19, 2021 – Shelved as: human-evolution
June 11, 2021 – Started Reading
June 23, 2021 – Shelved as: biological-evolution
June 23, 2021 – Finished Reading
August 25, 2021 – Shelved as: biology

Comments Showing 1-18 of 18 (18 new)

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message 1: by HBalikov (new)

HBalikov I am very interested in what you and Reich have to say about the mixing of various strains of humanity over time.


Orhan Pelinkovic Thank you, Balikov, for your comment. It's an important book to read and I look forward to sharing my thoughts in a couple of days when I finish it ;)


message 3: by Aurelia (new)

Aurelia Great review Orhan! Sounds fascinating!


Orhan Pelinkovic Aurelia wrote: "Great review Orhan! Sounds fascinating!"

Aurelia, thank you. It is a fascinating time we live in and we are lucky to have access to such technology that can reassemble the human migrations routes throughout history.


message 5: by Fran (new)

Fran Orhan...what a fascinating, informative review. Thank you!😊😎😁


message 6: by Ian (new)

Ian I agree with the comments from Fran and Aurelia!

The link between the native inhabitants of the Amazon and the indigenous peoples of Australia, New Guinea and the Andaman Islands was quite unexpected for me. Does this suggest a different migration from Eurasia from other Native Americans?


Orhan Pelinkovic Fran, thank you so much. Informative review for an informative book! This book is loaded with information. Btw. cool sunglasses :)


Orhan Pelinkovic Thank you, Ian! Unexpected, indeed. Reich doesn't answer all the questions and he leaves many gaps to be filled one day. Yes, he believes it's a separate population that migrated to the Americas that are a different people from the other Native Americans. He says that a migration of an ancient population happened, that he refers to as a ghost population; 'Population Y'. A population that no longer exists in unmixed form.


Marc Great review, Orhan. And thanks for the link. Adding to what you wrote in answer to Ian: indeed, paleogenetics is a very fast moving field. As Reich himself writes, even his book can’t offer all answers and it was outdated the moment it was published. Looking at how our view on genetics has evolved these last few years, there sure are more surprises to expect.


Orhan Pelinkovic Marc wrote: "Great review, Orhan. And thanks for the link. Adding to what you wrote in answer to Ian: indeed, paleogenetics is a very fast moving field. As Reich himself writes, even his book can’t offer all an..."

Thank you, Marc. It was a nice treat for me read a human evolution and human development book written in this century as most of the books I read are old (still playing catch-up). I can see Reich writing another book in the years to come with his latest research results but there are probably authors in Europe (Reich says Europe is at the forefront of genetics research and technology) and China to lookout for in the future. Although, it's more difficult to attain funding for paleogenetics work as most of the funds are allotted to genetic study strictly related to the pharmaceutical and medical industry.


message 11: by Libby (new)

Libby Truly fascinating review, Orhan! I just read of a discovery in a Russian cave of the 50,000 year old bone fragment of a child with a Neanderthal mother and a Denisovan father. What an interesting world our ancient Earth must have been,


Orhan Pelinkovic Why, thank you Libby for your generous comment :). Wow, that is an incredible and astonishing discovery! Yes, imagine that 50,000 years ago several archaic humankind's roomed the Earth. Talk about diversity!


message 13: by Annette (new)

Annette Fantastic review Orhan. I find it very fascinating how much we can learn from studying DNA. From what I understand, I think it's still a big puzzle to unravel, but at the same time we have learned so much. I watched some of it what you mention here in a documentary and it is a fascinating subject.


Orhan Pelinkovic Annette wrote: "Fantastic review Orhan. I find it very fascinating how much we can learn from studying DNA. From what I understand, I think it's still a big puzzle to unravel, but at the same time we have learned ..."

Thank you very much, Annette. Exactly, we only have a small pile of the pieces of this multilayered puzzle of human evolution, migration, and interbreeding, but brand-new ancient DNA laboratories are building every year and the technology and algorithms are being fine-tuned. So, I am expecting more surprises in the years to come :).


message 15: by Ilse (new)

Ilse A fascinating and thrilling write-up, Orhan - I very much liked your opening thought. On one side it is pretty amazing to read in the comments that recent research results already would add to such a recent book but it sounds a groundbreaking work.


message 16: by HBalikov (new)

HBalikov HBalikov wrote: "I am very interested in what you and Reich have to say about the mixing of various strains of humanity over time."

Another one of your very helpful reviews. Thanks!


Orhan Pelinkovic Ilse wrote: "A fascinating and thrilling write-up, Orhan - I very much liked your opening thought. On one side it is pretty amazing to read in the comments that recent research results already would add to such..."

Thank you so much, my fellow Yamnaya :). I do have a concern though, Ilse, that these results and future research will inevitably find that we are not all genetically the same, as we thought we were, and these scientists will end up grouping people by their genetic pattern and then will start to compare the groups characteristics and traits, which some will use as a handy tool for "scientifically backed" racial profiling. I hope that I am wrong.


Orhan Pelinkovic HBalikov wrote: "HBalikov wrote: "I am very interested in what you and Reich have to say about the mixing of various strains of humanity over time."

Another one of your very helpful reviews. Thanks!"


Thank you, Balikov, for your continuous support! This book is not an entertaining read but it was a learning experience and that's always fun :).


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