Honeymoon-bound newlyweds are killed in horror crash that orphaned their one-year-old son

A couple heading to their honeymoon after marrying only days earlier died in a horrific crash in Colorado that also killed the bride's mother and left their one-year-old child orphaned.  

Ruben Rodriguez, 33, and Juliana Rodriguez Plata, 37, were driving with their son and the bride's parents westbound down I-70 in Wheat Ridge outside Denver around 8:30am on Thursday when a semi-truck carry pipes overturned. 

The truck's load spilled across both sides of the highway, causing at least three vehicles to crash, Denver 7 reported. 

The bride's mother, Luz Melba Martinez, died while her father and young son, Daniel, survived with injuries. 

It is unclear what caused the truck to overturn. 

Ruben Rodriguez, 33, and Juliana Rodriguez Plata, 37, their son Daniel, and her parents were driving outside Denver on Thursday when a semi-truck carry pipes overturned

Ruben Rodriguez, 33, and Juliana Rodriguez Plata, 37, their son Daniel, and her parents were driving outside Denver on Thursday when a semi-truck carry pipes overturned

The truck's load spilled across both sides of the highway, causing at least three vehicles to crash

The truck's load spilled across both sides of the highway, causing at least three vehicles to crash

On Saturday, Rodriguez and Plata tied the knot and they had been traveling to the Colorado mountains for their honeymoon. 

'They were setting goals early for their kid, possibly have more children together and just had a normal life and just getting to begin their love story,' Rodriguez Plata's sister, Janell Rodriguez, told Denver 7. 

'We just want to know exactly what happened because they were on the other side of the highway. They weren't even near the semi-truck.' 

The newlyweds (pictured at center) and the bride's mother (at right) died in the crash, while the bride's father (at left) survived

The newlyweds (pictured at center) and the bride's mother (at right) died in the crash, while the bride'sfather (at left) survived

The couple's family launched a GoFundMe campaign to raise money for their funeral, as well as for Daniel and other expenses. 

'Luz Melba Martinez and Juliana’s father, Carlos, were here from Colombia to celebrate the wedding. Now, Carlos is faced with the unimaginable pain of losing both his daughter and wife in such a short span of time,' the description read.

DailyMail.com has contacted the family for comment.